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未成年穿山甲的婴儿血管瘤:一例报告。

Infantile hemangioma in a subadult Chinese pangolin: a case report.

机构信息

College of Animal Science and Technology, Zhongkai University of Agriculture and Engineering, Guangzhou, 510550, China.

Guangdong Provincial Key Laboratory of Silviculture, Protection and Utilization, Guangdong Academy of Forestry, Guangzhou, 510520, China.

出版信息

BMC Vet Res. 2024 Jan 24;20(1):31. doi: 10.1186/s12917-023-03832-9.

Abstract

BACKGROUND

Hemangiomas are a relatively common type of tumor in humans and animals. Various subtypes of hemangiomas have been described in the literature. The classification methods for hemangiomas differ between human and veterinary medicine, and the basis for tumor classification can be found in the literature.

CASE PRESENTATION

This study describes a tumor in the subcutaneous tissue of the right dorsum of an artificially rescued juvenile Chinese pangolin. Computed tomography (CT) examination yielded the preliminary diagnosis of a vascular malformation, and surgery was performed to resect the tumor. Histopathological examination showed that the tumor mainly was consisted of adipose tissue, capillaries, and spindle cells in the fibrous stroma. Immunohistochemistry showed the positive expression of CD31, CD34, α-SMA, GLUT1 and WT-1 in the tumor tissue, and the tumor was eventually diagnosed as an infantile haemangioma.

CONCLUSION

The final diagnosis of infantile hemangioma was depended on the histopathological immunohistochemical and CT examination of the neoplastic tissue. This is the first report of infantile hemangioma in a critically endangered species Chinese pangolin.

摘要

背景

血管瘤是人类和动物中相对常见的肿瘤类型。文献中已经描述了各种亚型的血管瘤。人类和兽医医学中的血管瘤分类方法不同,肿瘤分类的依据可以在文献中找到。

病例介绍

本研究描述了一只人工救助的幼年穿山甲右背部皮下组织中的肿瘤。计算机断层扫描(CT)检查初步诊断为血管畸形,并进行了手术切除肿瘤。组织病理学检查显示,肿瘤主要由脂肪组织、毛细血管和纤维基质中的梭形细胞组成。免疫组织化学显示肿瘤组织中 CD31、CD34、α-SMA、GLUT1 和 WT-1 阳性表达,最终诊断为婴儿血管瘤。

结论

婴儿血管瘤的最终诊断取决于肿瘤组织的组织病理学、免疫组织化学和 CT 检查。这是首例濒危物种穿山甲的婴儿血管瘤报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c5a/10807128/2ed21396fd3a/12917_2023_3832_Fig1_HTML.jpg

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