Institute of Veterinary Pathology, Justus-Liebig-University Giessen, Frankfurter Straße 96, 35392, Giessen, Germany.
Tierpraxis Schwarzach, Körnersbühnd 4, 77836, Rheinmünster, Germany.
BMC Vet Res. 2022 Dec 12;18(1):431. doi: 10.1186/s12917-022-03503-1.
Hemangioma is a well-known neoplasia in veterinary and human medicine. Several subtypes have been described and are distinguished based on their histologic appearance. The classification schemes of hemangiomas in human and veterinary medicine are different, and various purpose-based schemes can be found in the literature.
A six-week-old puppy was presented that suffered from a neoplasia that extended to the musculature of the hind limb. After surgical excision, the mass was submitted for pathohistological examination. The mass was composed of endothelial cells forming vascular slits admixed with a fibrous stroma and spindle cells. Immunohistological examination was positive for factor VIII-related antigen and smooth muscle actin, supporting the diagnosis of hemangioma.
The final diagnosis of granulation tissue-type hemangioma was given due to the histological appearance of the neoplasia. Granulation tissue-type hemangioma is a rare subtype of hemangioma. In this case an uncommonly young dog was affected.
血管瘤是兽医和人医中一种众所周知的肿瘤。已经描述了几种亚型，根据其组织学表现进行区分。人医和兽医中血管瘤的分类方案不同，文献中也可以找到各种基于目的的方案。
一只六周大的小狗出现了一种延伸到后肢肌肉的肿瘤。在进行手术切除后，将该肿块送检进行组织病理学检查。该肿块由形成血管裂隙的内皮细胞组成，混有纤维基质和平滑肌细胞。免疫组织化学检查因子 VIII 相关抗原和平滑肌肌动蛋白阳性，支持血管瘤的诊断。
由于肿瘤的组织学表现，最终诊断为肉芽组织型血管瘤。肉芽组织型血管瘤是一种罕见的血管瘤亚型。在本例中，一只非常年轻的狗受到了影响。
