Timoshko M A, Vil'shanskaia F L, Pospelova V V, Rakhimova N G
Zh Mikrobiol Epidemiol Immunobiol. 1979 Jul(7):92-6.
The antagonistic relations between Bacterium bifidum, strain I/850 phi, and Proteus vulgaris, strain F-30, were studied. These organisms, when introduced together in equal doses into the digestive tract of gnotobiotic chickens in a single administration, were shown to create certain ecological correlations in various organs with the prevalence of bifidobacteria which exerted no negative influence on Proteus vulgaris. The additional daily administration of bifidobacteria for 3 days running in doses 1000 times as great as the initial dose, the content of both dibifobacteria and Proteus vulgaris in the intestine being at that time at its maximum, resulted in the suppression of the growth of Proteus vulgaris. Our findings indicate that the influence of the pH of the medium should be considered in order to obtain the evidence of significantly pronounced antagonistic relations between the two organisms in vitro.
对双歧杆菌I/850株与普通变形杆菌F-30株之间的拮抗关系进行了研究。当将这些微生物以等量单次引入无菌鸡的消化道时，结果表明它们在各个器官中形成了特定的生态关联，双歧杆菌占优势，且对普通变形杆菌没有负面影响。连续3天每天额外给予剂量比初始剂量大1000倍的双歧杆菌，此时肠道中双歧杆菌和普通变形杆菌的含量均处于最高水平，结果导致普通变形杆菌的生长受到抑制。我们的研究结果表明，为了在体外获得这两种微生物之间明显显著的拮抗关系的证据，应考虑培养基pH值的影响。
