Albrecht S, Thuy L T, Pasternak G, Schlott B, Reinhöfer J, Lunow E, Loewe G, Gütz H J
Acta Biol Med Ger. 1978;37(11-12):1747-57.
The sensitization of lymphocytes from patients with different tumors was tested against a 3 M KCl-extract of fetal tissue (3.--6. month) by the leukocyte adherence inhibition assay (LAI) and by the leukocyte migration inhibition assay (LMI). Sensitization was compared with the reactivity of controls without any detectable tumor. In the LAI assay the leukocytes of 13/15 patients and 2/12 controls showed an inhibition of the adherence. In the LMI-assay 11/17 tumor-bearing patients and 6/18 controls reacted positive in the presence of the antigen preparation. The two methods demonstrated that patients bearing tumors of different histology are sensitized to fetal antigens.
通过白细胞黏附抑制试验（LAI）和白细胞游走抑制试验（LMI），检测不同肿瘤患者的淋巴细胞对胎儿组织（3 - 6个月）的3M氯化钾提取物的致敏情况。将致敏情况与未检测到肿瘤的对照组的反应性进行比较。在LAI试验中，15例患者中的13例以及12例对照组中的2例白细胞黏附受到抑制。在LMI试验中，17例肿瘤患者中的11例以及18例对照组中的6例在抗原制剂存在的情况下反应呈阳性。这两种方法表明，患有不同组织学类型肿瘤的患者对胎儿抗原有致敏反应。
