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以胎儿组织的3M氯化钾提取物作为抗原,对肿瘤患者进行白细胞黏附抑制试验。

The leukocyte adherence inhibition test in tumor patients using 3M KCl extracts of fetal tissues as antigens.

作者信息

Albrecht S, Schlott B, Pasternak G, Reinhöfer J, Lunow G

出版信息

Arch Geschwulstforsch. 1982;52(5):341-8.

PMID:7149907
Abstract

The sensitization of tumor patients was evaluated with the LAI test to 3M KCl extracts of human fetuses derived from abortion in the 1st-3rd month, 5th month and 7th month of pregnancy. Positive responses were seen against preparations from fetuses at different developmental stages: reactivity was found among 12/18 (1st-3rd month), 13/15 (5th month) and 14/16 (7th month) of the tumor patients. In total, 80% (39/49) of the patients were sensitized to fetal extracts. In contrast, only 19% (10/54) of the control group reacted positively in the LAI test.

摘要

通过淋巴细胞转化试验(LAI试验)评估肿瘤患者对源自妊娠第1 - 3个月、第5个月和第7个月流产胎儿的3M氯化钾提取物的致敏情况。在不同发育阶段的胎儿提取物中均观察到阳性反应:在肿瘤患者中,对第1 - 3个月胎儿提取物有反应的占12/18,对第5个月胎儿提取物有反应的占13/15,对第7个月胎儿提取物有反应的占14/16。总体而言,80%(39/49)的患者对胎儿提取物敏感。相比之下,对照组中只有19%(10/54)在LAI试验中呈阳性反应。

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