Abtahi Firoozeh, Atashbarg Malek, Rahmanian Mahdi, Moeinvaziri Nader, Bazrafshan Mehdi, Bazrafshan Hanieh, Moammer Farzaneh, Bazroodi Helia, Zolghadrasli Abdolali, Bazrafshan Drissi Hamed
Department of Cardiology, School of Medicine, Shiraz University of Medical Science, Shiraz, Iran.
Cardiovascular research center, Shiraz university of medical science, Shiraz, Iran.
BMC Surg. 2024 Jan 25;24(1):37. doi: 10.1186/s12893-024-02328-z.
Obesity is a pathology and a leading cause of death worldwide. Obesity can harm multiple organs, including the heart. In this study, we aim to investigate the effect of bariatric surgery and following weight loss on cardiac structure and functions using echocardiography parameters in patients with morbid obesity.
In this cohort study, 30 patients older than 18 with BMI > 40 or BMI > 35 and comorbidity between March 2020 to March 2021 were studied. The patients underwent transthoracic echocardiography before and after six months of the bariatric surgery.
In total, 30 patients (28 women, 93.3%) with a mean age of 38.70 ± 9.19 were studied. Nine (30%) were diabetic, and 9 (30%) had hypertension. After six months of bariatric surgery, all physical measurements, including weight, Body mass index, and Body surface area, decreased significantly (p < 0.001). After bariatric surgery, all parameters regarding left ventricular morphology, including left ventricular mass, interventricular septal thickness, left ventricular posterior wall thickness, left ventricular end-systolic diameter, and left ventricular end-diastolic diameter, improved significantly (p < 0.001). Also, LVEF rose post-bariatric surgery (p < 0.001). TAPSE parameter indicating right ventricular function also improved (p < 0.001). Right ventricular diameter, left atrium volume, and mitral inflow E/e decreased significantly (p < 0.001).
Systolic and diastolic parameters refine significantly after bariatric surgery in patients with obesity. Bariatric surgery lead to significant cardiac structure and function improvement.
肥胖是一种病理状态，也是全球主要的死亡原因。肥胖会损害包括心脏在内的多个器官。在本研究中，我们旨在使用超声心动图参数，研究减肥手术及随后的体重减轻对病态肥胖患者心脏结构和功能的影响。
在这项队列研究中，对2020年3月至2021年3月期间30名年龄大于18岁、BMI>40或BMI>35且伴有合并症的患者进行了研究。这些患者在减肥手术前和术后六个月接受了经胸超声心动图检查。
总共研究了30名患者（28名女性，占93.3%），平均年龄为38.70±9.19岁。9名（30%）患有糖尿病，9名（30%）患有高血压。减肥手术后六个月，所有身体测量指标，包括体重、体重指数和体表面积，均显著下降（p<0.001）。减肥手术后，所有与左心室形态相关的参数，包括左心室质量、室间隔厚度、左心室后壁厚度、左心室收缩末期直径和左心室舒张末期直径，均有显著改善（p<着0.001）。此外，减肥手术后左心室射血分数升高（p<0.001）。表明右心室功能的三尖瓣环平面收缩期位移参数也有所改善（p<0.001）。右心室直径、左心房容积和二尖瓣流入E/A比值显著下降（p<0.001）。
肥胖患者减肥手术后收缩期和舒张期参数明显改善。减肥手术可显著改善心脏结构和功能。
