地西泮所致过敏性间质性肾炎

Allergic interstitial nephritis due to diazepam.

作者信息

Sadjadi S A, McLaughlin K, Shah R M

出版信息

Arch Intern Med. 1987 Mar;147(3):579. doi: 10.1001/archinte.147.3.579.

DOI:10.1001/archinte.147.3.579

Abstract

A 56-year-old man developed allergic interstitial nephritis and deterioration of preexisting chronic renal failure after receiving diazepam. On discontinuation of diazepam, kidney function returned to the baseline level and itching, eosinophilia, and eosinophiluria subsided. A causative correlation between allergic interstitial nephritis and diazepam is suggested.

摘要

一名56岁男性在服用地西泮后出现过敏性间质性肾炎，原有慢性肾衰竭病情恶化。停用地西泮后，肾功能恢复至基线水平，瘙痒、嗜酸性粒细胞增多及嗜酸性粒细胞尿症状消退。提示过敏性间质性肾炎与地西泮之间存在因果关系。