与环丙沙星相关的过敏性肾病。

Allergic nephropathy associated with ciprofloxacin.

作者信息

Rastogi S, Atkinson J L, McCarthy J T

机构信息

Division of Nephrology and Internal Medicine, Mayo Clinic, Rochester, MN 55905.

出版信息

Mayo Clin Proc. 1990 Jul;65(7):987-9. doi: 10.1016/s0025-6196(12)65160-x.

DOI:10.1016/s0025-6196(12)65160-x

PMID:2376981

Abstract

We report a case of ciprofloxacin-related allergic tubulointerstitial nephritis, which manifested as nonoliguric renal failure, eosinophilia, and eosinophiluria. Our patient responded to discontinuation of ciprofloxacin therapy and oral administration of a brief course of corticosteroids. Although rare, allergic tubulointerstitial nephritis apparently can be caused by ciprofloxacin therapy. Clinicians should be aware of this entity.

摘要

我们报告了一例环丙沙星相关的过敏性肾小管间质性肾炎病例，其表现为非少尿性肾衰竭、嗜酸性粒细胞增多和嗜酸性粒细胞尿。我们的患者在停用环丙沙星治疗并口服短期皮质类固醇后病情好转。尽管罕见，但过敏性肾小管间质性肾炎显然可由环丙沙星治疗引起。临床医生应了解这一病症。