Ranieri Maurizio, Marvulli Riccardo, D'Alesio Eleonora, Riccardi Mariagrazia, Raele Maria Vittoria, Dell'Anna Laura, Fai Annatonia, Farì Giacomo, Megna Marisa
Department of Translational Biomedicine and Neuroscience (DiBraiN), Aldo Moro University, G. Cesare Place 11, 70125 Bari, Italy.
Department of Biological and Environmental Science and Technologies (Di.S.Te.B.A.), University of Salento, 73100 Lecce, Italy.
J Pers Med. 2024 Jan 22;14(1):122. doi: 10.3390/jpm14010122.
Mesotherapy is a procedure or a process of injecting drugs into the skin. This technique can help decrease the total drug dose due to its drug-sparing effect on the systemic route and can be utilized to treat nonspecific neck pain that occurs in the lateral and posterior neck.
Ten patients with bilateral cervicobrachial pain were recruited and evaluated at T0 before treatments, T1 at the end of the treatment (42 days after T0), and T2 (72 days after T0). Assessments consisted of performing the Visual Analogue Scale (VAS) to evaluate pain evolution; a range of movement (ROM) and Bilateral trapezius' tone, elasticity, and dynamic stiffness mensuration were performed using MyotonPro. All patients underwent mesotherapy treatment in the trapezius muscles with 1 cc of Diclofenac Sodium and 1 cc of lidocaine diluted in 3 cc of saline for a total of 6 weeks.
VAS value statistically decreased at T1 and T2; ROM of neck flexion statistically increased at T1 and T2, and miometric tone and stiffness value statistically improved at T1 and T2.
mesotherapy with Diclofenac Sodium reduced pain intensity and improved functional outcomes, with no significant adverse effects in patients with myofascial pain syndrome of cervicobrachial localization.
中胚层疗法是一种将药物注入皮肤的操作或过程。由于其对全身给药途径的药物节省作用,该技术有助于减少药物总剂量,可用于治疗发生在颈部外侧和后部的非特异性颈部疼痛。
招募了10名双侧颈臂疼痛患者,在治疗前的T0、治疗结束时(T0后42天)的T1以及T2(T0后72天)进行评估。评估包括使用视觉模拟量表(VAS)评估疼痛演变;使用MyotonPro进行一系列运动范围(ROM)以及双侧斜方肌的张力、弹性和动态僵硬度测量。所有患者在斜方肌接受中胚层疗法治疗,将1毫升双氯芬酸钠和1毫升利多卡因稀释于3毫升生理盐水中,共治疗6周。
VAS值在T1和T2时统计学上显著降低;颈部前屈的ROM在T1和T2时统计学上显著增加,肌张力和僵硬度值在T1和T2时统计学上显著改善。
双氯芬酸钠中胚层疗法降低了疼痛强度,改善了功能结局,对颈臂部肌筋膜疼痛综合征患者无明显不良反应。