Kmieciak Anna, Krzemiński Marek P, Hodii Anastasiia, Gorczyca Damian, Jastrzębska Aneta
Faculty of Chemistry, Nicolaus Copernicus University in Torun, 7 Gagarin Str., 87-100 Torun, Poland.
Faculty of Medicine, Lazarski University, 43 Świeradowska Str., 02-662 Warsaw, Poland.
Materials (Basel). 2024 Jan 22;17(2):520. doi: 10.3390/ma17020520.
In this paper, a highly efficient and straightforward method for synthesizing novel Schiff bases was developed by reacting selected biogenic amines with sodium 2-formylbenzene sulfonate and sodium 3-formylbenzene sulfonate. H and C NMR, IR spectroscopy, and high-resolution mass spectrometry were used to characterize the new compounds. The main advantages of the proposed procedure include simple reagents and reactions carried out in water or methanol and at room temperature, which reduces time and energy. Moreover, it was shown that the obtained water-soluble Schiff bases are stable in aqueous solution for at least seven days. Additionally, the antioxidant and antimicrobial activity of synthesized Schiff bases were tested.
在本文中，通过将选定的生物胺与2-甲酰基苯磺酸钠和3-甲酰基苯磺酸钠反应，开发了一种高效且直接的合成新型席夫碱的方法。利用氢核磁共振（H NMR）、碳核磁共振（C NMR）、红外光谱（IR）和高分辨率质谱对新化合物进行了表征。所提出方法的主要优点包括试剂简单，反应在水或甲醇中于室温下进行，这减少了时间和能源。此外，结果表明所获得的水溶性席夫碱在水溶液中至少稳定七天。另外，还测试了合成席夫碱的抗氧化和抗菌活性。
