Long Fen, Jiang Kai, Song Weiwei, Luo Wenkun, Yin Biaolin
Key Laboratory of Functional Molecular Engineering of Guangdong Province, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong 510640, China.
Hunan Provincial Key Laboratory of Cytochemistry, School of Chemistry and Chemical Engineering, Changsha University of Science and Technology, Changsha 410114, China.
Org Lett. 2024 Feb 9;26(5):1083-1087. doi: 10.1021/acs.orglett.3c04345. Epub 2024 Jan 26.
We report an efficient and mild approach for radical dearomatization via photoinduced palladium-catalyzed reaction of three components (i.e., furans, alcohols, and bromoalkanes). In this strategy, various functionalized spiro-heterocycles were prepared from furans in one step via cascade C-C/C-O bond formation under redox neutral conditions.
我们报道了一种通过光诱导钯催化的三组分（即呋喃、醇和溴代烷烃）反应实现自由基去芳构化的高效温和方法。在该策略中，各种官能化的螺杂环在氧化还原中性条件下通过级联C-C/C-O键形成一步从呋喃制备得到。
