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肠闭锁:十年结局评估。

Intestinal Atresias: A Ten-Year Evaluation of Outcomes.

机构信息

Department of Pediatric Surgery, Children's of Alabama, Birmingham, AL; Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.

Department of Pediatric Surgery, Children's of Alabama, Birmingham, AL; Department of Surgery, University of Alabama at Birmingham, Birmingham, AL.

出版信息

J Surg Res. 2024 Apr;296:130-134. doi: 10.1016/j.jss.2023.12.015. Epub 2024 Jan 25.

Abstract

INTRODUCTION

Intestinal atresia is a common cause of neonatal bowel obstruction. Atresias are often associated with other congenital anomalies. The purpose of the study was to evaluate associated anomalies, operative management, and postoperative outcomes of infants with intestinal atresia.

METHODS

A review of patients presenting to a single free-standing children's hospital from March 2012 through February 2022 was performed. The variables examined were type of atresia, additional congenital anomalies, type of operative intervention, and postoperative outcomes. Standard statistical methods were utilized.

RESULTS

A total of 75 patients with intestinal atresia were identified and several of these patients had multiple atresias. Isolated duodenal atresia patients were the most common (49.3%), followed by jejunal (32%) and ileal (12%). Mixed atresias were rare at 4%, with isolated pyloric and colonic also rare at 1.3% each. Malrotation was associated with 13% of patients and equally associated with duodenal and jejunoileal atresias. A low percentage (3%) of intestinal atresias was seen in conjunction with gastroschisis and concomitant malrotation. A majority of infants with duodenal atresia underwent standard duodenoduodenostomy (19% laparoscopic, 81% open). In infants with jejunoileal atresia, most underwent resection with primary anastomosis. A tapering enteroplasty was performed primarily in 13% of atresias. There were no significant differences noted in time to first feed or length of stay between those with and without tapering enteroplasty. Eleven percent of patients required subsequent intervention for stricture or small bowel obstruction. There was one death in this series.

CONCLUSIONS

Consistent with other literature, duodenal atresia was the most common type of intestinal atresia. However, we demonstrated that malrotation was equally associated with duodenal and jejunoileal atresias while prior reports had shown a higher association with duodenal atresia. In our patient population, the use of tapering enteroplasty did not appear to be associated with outcomes. Overall, these infants have a low morbidity and mortality rate with a rare need for reoperation.

摘要

引言

肠闭锁是新生儿肠梗阻的常见原因。闭锁常伴有其他先天性畸形。本研究旨在评估肠闭锁患儿的伴发畸形、手术治疗和术后结果。

方法

对 2012 年 3 月至 2022 年 2 月期间在一家独立的儿童医院就诊的患者进行了回顾性分析。检查的变量包括闭锁类型、其他先天性畸形、手术干预类型和术后结果。采用标准统计学方法。

结果

共发现 75 例肠闭锁患儿,其中部分患儿存在多种闭锁。孤立性十二指肠闭锁患儿最常见(49.3%),其次是空肠(32%)和回肠(12%)。混合性闭锁罕见,占 4%,孤立性幽门和结肠闭锁也罕见,各占 1.3%。肠旋转不良与 13%的患儿有关,与十二指肠和空肠回肠闭锁的发生率相同。肠闭锁与先天性腹裂和伴发肠旋转不良的比例较低(3%)。大多数十二指肠闭锁患儿行标准十二指肠吻合术(19%腹腔镜,81%开腹)。空肠回肠闭锁患儿多采用肠切除端端吻合术。在 13%的闭锁患儿中采用了缩窄肠成形术。有缩窄肠成形术的患儿与无缩窄肠成形术的患儿在首次喂养时间和住院时间方面无显著差异。11%的患儿因狭窄或小肠梗阻需要再次手术。本系列中有 1 例死亡。

结论

与其他文献一致,十二指肠闭锁是最常见的肠闭锁类型。然而,我们发现肠旋转不良与十二指肠和空肠回肠闭锁的发生率相同,而之前的报告显示与十二指肠闭锁的相关性更高。在我们的患者人群中,使用缩窄肠成形术似乎与结果无关。总体而言,这些患儿的发病率和死亡率较低,再次手术的需求罕见。

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