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电化学生物传感器在应激标志物检测方面的最新进展

Recent Advances in Electrochemical Biosensors Targeting Stress Markers.

机构信息

Department of Pharmacognosy, KIET School of Pharmacy, KIET Group of Institutions, Delhi-NCR, Ghaziabad, 201206, Uttar Pradesh, India.

Department of Electronics and Communication Engineering, ABES Engineering College, 19th KM Stone, NH-09 Ghaziabad, 201009, Uttar Pradesh, India.

出版信息

Comb Chem High Throughput Screen. 2024;27(13):1877-1886. doi: 10.2174/0113862073278547231210170007.

DOI:10.2174/0113862073278547231210170007
PMID:38279751
Abstract

INTRODUCTION

When the body experiences a change in its internal environment due to factors such as mood (euphoria, stress) and illness, it releases biomarkers in large quantities. These biomarkers are used for detecting a disease at its early stages. This involves the detection of insufficient quantities of biocomponents, which can be done by using nanomaterials, conventional materials, and biotechnology; thus, scientists can increase the sensitivity of electrochemical sensors. According to studies conducted in this area, electrochemical sensors have shown promise as a diagnostic tool due to their ability to identify and pinpoint illness biomarkers. The present review article was compiled to gather the latest information on electrochemical biosensors targeting stress markers.

MATERIALS AND METHODS

The authors searched scholarly databases like ScienceDirect, Pubmed, Medline, and Scopus for information on electrochemical biosensors targeting stress markers.

RESULTS

In this article, we looked at the recent developments in electrochemical sensors for stress monitoring. Because of advances in nanomaterial and biomolecule processes, electrochemical biosensors have been developed with the sensitivity to detect several biomarkers in real-time in therapeutically relevant materials.

CONCLUSION

This biomarker sensor strategy can analyze various biofluids (sweat, plasma, urine, and saliva).

摘要

简介

当身体因情绪(欣快、压力)和疾病等因素而经历内部环境变化时,它会大量释放生物标志物。这些生物标志物可用于在疾病早期进行检测。这涉及到检测生物成分的数量不足,可以通过使用纳米材料、常规材料和生物技术来实现;因此,科学家可以提高电化学传感器的灵敏度。根据该领域的研究,电化学传感器已显示出作为诊断工具的潜力,因为它们能够识别和精确定位疾病生物标志物。本文综述了针对应激标志物的电化学生物传感器的最新信息。

材料和方法

作者在 ScienceDirect、Pubmed、Medline 和 Scopus 等学术数据库中搜索了针对应激标志物的电化学生物传感器的信息。

结果

本文着眼于用于应激监测的电化学传感器的最新发展。由于纳米材料和生物分子处理方面的进步,电化学生物传感器已经发展出了足够的灵敏度,可在治疗相关材料中实时检测多种生物标志物。

结论

这种生物标志物传感器策略可以分析各种生物流体(汗液、血浆、尿液和唾液)。

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