口服布洛芬治疗早产儿动脉导管未闭：迫切需要一种比高渗制剂更安全的替代药物。 - Suppr

Oral Ibuprofen for the Treatment of PDA in Preterm Neonates: Urgent Need for a Safer Alternative to Hyperosmolar Formulations.

作者信息

Del Rosario Jaemaela, Fusch Gerhard, McBryde Ali, Sushko Katelyn, van den Anker John, Samiee-Zafarghandy Samira

机构信息

Neonatal Intensive Care Unit, McMaster Children's Hospital, Hamilton, ON, Canada.

Department of Pediatrics, Division of Neonatology, McMaster University, 1280 Main Street West, Hamilton, ON, L8S 4 L8, Canada.

出版信息

Paediatr Drugs. 2024 Mar;26(2):205-207. doi: 10.1007/s40272-023-00617-3. Epub 2024 Jan 27.

DOI:10.1007/s40272-023-00617-3

PMID:38280107

Abstract

摘要

相似文献

Oral Ibuprofen for the Treatment of PDA in Preterm Neonates: Urgent Need for a Safer Alternative to Hyperosmolar Formulations.口服布洛芬治疗早产儿动脉导管未闭：迫切需要一种比高渗制剂更安全的替代药物。

Paediatr Drugs. 2024 Mar;26(2):205-207. doi: 10.1007/s40272-023-00617-3. Epub 2024 Jan 27.

Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants.布洛芬用于治疗早产或低出生体重（或两者兼具）婴儿的动脉导管未闭。

Cochrane Database Syst Rev. 2018 Sep 28;9(9):CD003481. doi: 10.1002/14651858.CD003481.pub7.

Cochrane Database Syst Rev. 2015 Feb 18(2):CD003481. doi: 10.1002/14651858.CD003481.pub6.

Ibuprofen for the treatment of patent ductus arteriosus in preterm or low birth weight (or both) infants.布洛芬用于治疗早产或低体重（或两者兼具）婴儿的动脉导管未闭。

Cochrane Database Syst Rev. 2020 Feb 11;2(2):CD003481. doi: 10.1002/14651858.CD003481.pub8.

Cost-effectiveness of Oral Versus Intravenous Ibuprofen Therapy in Preterm Infants With Patent Ductus Arteriosus in the Neonatal Intensive Care Setting: A Cohort-based Study.静脉注射与口服布洛芬治疗在新生儿重症监护病房中患有动脉导管未闭早产儿的成本效益：一项基于队列的研究。

Clin Ther. 2021 Feb;43(2):336-348.e7. doi: 10.1016/j.clinthera.2020.12.004. Epub 2021 Jan 9.

Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants.布洛芬用于治疗早产和/或低出生体重婴儿的动脉导管未闭。

Cochrane Database Syst Rev. 2008 Jan 23(1):CD003481. doi: 10.1002/14651858.CD003481.pub3.

Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low-birth-weight infants.对乙酰氨基酚（扑热息痛）用于早产儿或低体重儿动脉导管未闭的治疗。

Cochrane Database Syst Rev. 2015 Mar 11(3):CD010061. doi: 10.1002/14651858.CD010061.pub2.

Efficacy and tolerability of enteral formulations of ibuprofen in the treatment of patent ductus arteriosus in preterm infants.布洛芬肠内制剂治疗早产儿动脉导管未闭的疗效和耐受性。

Clin Ther. 2010 Sep;32(10):1740-8. doi: 10.1016/j.clinthera.2010.08.011.

Closure of patent ductus arteriosus with oral ibuprofen suspension in premature newborns: a pilot study.口服布洛芬混悬液用于早产儿动脉导管未闭的闭合：一项初步研究。

Pediatrics. 2003 Nov;112(5):e354. doi: 10.1542/peds.112.5.e354.

Paracetamol (acetaminophen) for patent ductus arteriosus in preterm or low birth weight infants.对乙酰氨基酚（醋氨酚）用于早产儿或低出生体重儿动脉导管未闭。

Cochrane Database Syst Rev. 2018 Apr 6;4(4):CD010061. doi: 10.1002/14651858.CD010061.pub3.

本文引用的文献

Management of Patent Ductus Arteriosus in Premature Infants in 2020.2020年早产儿动脉导管未闭的管理

Front Pediatr. 2021 Feb 11;8:590578. doi: 10.3389/fped.2020.590578. eCollection 2020.

Osmolality of Commonly Used Oral Medications in the Neonatal Intensive Care Unit.新生儿重症监护病房常用口服药物的渗透压

J Pediatr Pharmacol Ther. 2021;26(2):172-178. doi: 10.5863/1551-6776-26.2.172. Epub 2021 Feb 15.

Feeding Formula Eliminates the Necessity of Bacterial Dysbiosis and Induces Inflammation and Injury in the Paneth Cell Disruption Murine NEC Model in an Osmolality-Dependent Manner.喂养配方以渗透压依赖的方式消除了细菌失调的必要性，并在潘氏细胞破坏的 NEC 模型中诱导了炎症和损伤。

Nutrients. 2020 Mar 26;12(4):900. doi: 10.3390/nu12040900.

Pharmacological closure of the patent ductus arteriosus: when treatment still makes sense.动脉导管未闭的药物性闭合：何时治疗仍有意义。

J Perinatol. 2019 Nov;39(11):1439-1441. doi: 10.1038/s41372-019-0518-3. Epub 2019 Oct 7.

Hyperosmolar environment and intestinal epithelial cells: impact on mitochondrial oxygen consumption, proliferation, and barrier function in vitro.高渗环境与肠上皮细胞：对体外线粒体耗氧、增殖和屏障功能的影响。

Sci Rep. 2019 Aug 6;9(1):11360. doi: 10.1038/s41598-019-47851-9.

Association of Placebo, Indomethacin, Ibuprofen, and Acetaminophen With Closure of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Infants: A Systematic Review and Meta-analysis.安慰剂、吲哚美辛、布洛芬和对乙酰氨基酚与早产儿血流动力学显著的动脉导管未闭闭合的关联：一项系统评价和荟萃分析。

JAMA. 2018 Mar 27;319(12):1221-1238. doi: 10.1001/jama.2018.1896.

Current Knowledge of Necrotizing Enterocolitis in Preterm Infants and the Impact of Different Types of Enteral Nutrition Products.早产儿坏死性小肠结肠炎的当前认知以及不同类型肠内营养产品的影响

Adv Nutr. 2017 Jan 17;8(1):80-91. doi: 10.3945/an.116.013193. Print 2017 Jan.

Gut blood flow velocities in the newborn: effects of patent ductus arteriosus and parenteral indomethacin.新生儿肠道血流速度：动脉导管未闭及胃肠外吲哚美辛的影响

Arch Dis Child. 1990 Oct;65(10 Spec No):1067-71. doi: 10.1136/adc.65.10_spec_no.1067.

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Oral Ibuprofen for the Treatment of PDA in Preterm Neonates: Urgent Need for a Safer Alternative to Hyperosmolar Formulations.

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