State Key Laboratory of Crop Stress Resistance and High-Efficiency Production, College of Agronomy, Northwest A&F University, Yangling 712100, China.
National Key Laboratory of Agricultural Microbiology, Hubei Hongshan Laboratory, Hubei Key Laboratory of Plant Pathology, College of Plant Science and Technology, Huazhong Agricultural University, Wuhan 430070, China.
Phytopathology. 2024 Jun;114(6):1215-1225. doi: 10.1094/PHYTO-08-23-0269-R. Epub 2024 Jun 12.
is the causal agent of broomcorn millet () smut disease, which results in serious yield losses in broomcorn millet production. However, the molecular basis underlying broomcorn millet defense against is less understood. In this study, we investigated how broomcorn millet responds to infection by by employing a comprehensive multi-omics approach. We examined the responses of broomcorn millet across transcriptome, metabolome, and microbiome levels. Infected leaves exhibited an upregulation of genes related to photosynthesis, accompanied by a higher accumulation of photosynthesis-related compounds and alterations in hormonal levels. However, broomcorn millet genes involved in immune response were downregulated post infection, suggesting that may suppress broomcorn millet immunity. In addition, we show that the immune suppression and altered host metabolism induced by have no significant effect on the microbial community structure of broomcorn millet leaf, thus providing a new perspective for understanding the tripartite interaction between plant, pathogen, and microbiota.
是黍（）黑粉病的病原体，可导致黍生产中严重减产。然而，黍抵抗的分子基础知之甚少。在这项研究中，我们采用了一种全面的多组学方法来研究黍对 的反应。我们检测了黍在转录组、代谢组和微生物组水平上的反应。受感染的叶片表现出与光合作用相关的基因上调，伴随着与光合作用相关的化合物积累增加和激素水平的改变。然而，感染后与免疫反应相关的黍基因被下调，表明 可能抑制黍的免疫。此外，我们还表明， 诱导的免疫抑制和宿主代谢改变对黍叶片微生物群落结构没有显著影响，从而为理解植物、病原体和微生物群落之间的三方相互作用提供了新的视角。
