Cosci Fiammetta, Christensen Kaj Sparle, Ceccatelli Sara, Patierno Chiara, Carrozzino Danilo
Department of Health Sciences, University of Florence, Florence, Italy. International Lab of Clinical Measurements, University of Florence, Florence, Italy. Department of Psychiatry & Neuropsychology, Maastricht University, Maastricht, The Netherlands.
Research Unit for General Practice and Section for General Medical Practice, Department of Public Health, Aarhus University, Aarhus, Denmark.
Braz J Psychiatry. 2024;46:e20233449. doi: 10.47626/1516-4446-2023-3449. Epub 2024 Jan 28.
The Patient Health Questionnaire-9 (PHQ-9) is a widely used self-report measure of depression whose psychometric properties were found to be merely acceptable. Insufficient attention has been devoted to its clinimetric validity, while its clinical utility is still debated, particularly for assessing depression severity. This is the first study to test the PHQ-9 construct validity and clinical utility based on clinimetric principles.
An online survey of 3,398 participants was conducted. Item response theory models (Rasch and Mokken analyses) were used to assess the PHQ-9 validity and determine its clinical utility.
Fit to the Rasch model was achieved after adjusting the sample size. Items 2, 4, 6, and 9 over-discriminated, while items 1, 5, and 7 under-discriminated. Local dependency between items 2 and 6 was indicated. The PHQ-9 was not unidimensional. A Loevinger's coefficient of 0.49 was found, indicating an acceptable level of scalability.
The PHQ-9 is an instrument with potential clinical utility as an overall index of depression, mainly for screening purposes. Substantial revision, particularly in the wording of over- and under-discriminating items, is needed.
患者健康问卷-9(PHQ-9)是一种广泛使用的抑郁症自评量表,但其心理测量特性仅被认为尚可接受。对其临床计量学效度的关注不足,而其临床效用仍存在争议,尤其是在评估抑郁严重程度方面。这是第一项基于临床计量学原理检验PHQ-9结构效度和临床效用的研究。
对3398名参与者进行了在线调查。使用项目反应理论模型(拉施分析和莫肯分析)评估PHQ-9的效度并确定其临床效用。
在调整样本量后,该量表符合拉施模型。第2、4、6和9项过度区分,而第1、5和7项区分不足。显示第2项和第6项之间存在局部依赖性。PHQ-9并非单维量表。发现洛温杰系数为0.49,表明具有可接受的可扩展性水平。
PHQ-9作为抑郁症的总体指标具有潜在的临床效用,主要用于筛查目的。需要进行实质性修订,特别是在过度区分和区分不足项目的措辞方面。