Hirai Masahiro, Ikeda Ayaka, Kato Takeo, Ikeda Takahiro, Asada Kosuke, Hakuno Yoko, Matsushima Kanae, Awaya Tomonari, Okazaki Shin, Kato Toshihiro, Heike Toshio, Hagiwara Masatoshi, Yamagata Takanori, Tomiwa Kiyotaka, Kimura Ryo
Department of Cognitive and Psychological Sciences, Graduate School of Informatics, Nagoya University, Furo- cho, Chikusa-ku, Nagoya, 464-8601, Japan.
Center for Development of Advanced Medical Technology, Jichi Medical University, Tochigi, Japan.
J Autism Dev Disord. 2025 Jun;55(6):2092-2099. doi: 10.1007/s10803-023-06205-1. Epub 2024 Jan 28.
With the current study, we aimed to reveal the similarities and differences in sensory profiles between Williams syndrome (WS) and autism spectrum disorder.
Using the sensory profile questionnaire completed by the caregivers, we analyzed the WS (n = 60, 3.4-19.8 years) and autistic (n = 39, 4.2-14.0 years) groups.
The Severity Analysis revealed a significant group difference in Sensory Sensitivity but not in Low Registration, Sensation Seeking, and Sensation Avoiding subscales. Age can modulate the subscale scores differently across groups. For Sensation Seeking, the scores of both groups decreased with development. However, the scores of Sensory Sensitivity decreased with age in the autistic group but not in the WS group. Sensation Avoiding scores increased with development in the WS group but not in the autistic group. No significant developmental changes were observed in Low Registration.
This study highlights the cross-syndrome similarities and differences in sensory profiles and developmental changes in autistic individuals and individuals with WS.
通过本研究,我们旨在揭示威廉姆斯综合征(WS)和自闭症谱系障碍在感觉特征方面的异同。
我们使用由照料者填写的感觉特征问卷,对WS组(n = 60,年龄3.4 - 19.8岁)和自闭症组(n = 39,年龄4.2 - 14.0岁)进行了分析。
严重程度分析显示,两组在感觉敏感性方面存在显著差异,但在低反应性、感觉寻求和感觉回避子量表方面不存在显著差异。年龄对不同组的子量表得分有不同的调节作用。对于感觉寻求,两组得分均随发育而降低。然而,自闭症组的感觉敏感性得分随年龄降低,而WS组则不然。WS组的感觉回避得分随发育增加,而自闭症组则不然。在低反应性方面未观察到显著的发育变化。
本研究突出了自闭症个体和WS个体在感觉特征及发育变化方面的跨综合征异同。