Department of Rehabilitation Medicine, Nagasaki University Hospital, Nagasaki, Japan; Department of Physical Therapy Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Department of Nursing, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Respir Investig. 2024 Mar;62(2):291-294. doi: 10.1016/j.resinv.2024.01.006. Epub 2024 Jan 28.
This retrospective observational study aimed to assess the clinical characteristics of platypnea-orthodeoxia syndrome in patients with coronavirus disease 2019 (COVID-19) treated using mechanical ventilation or high-flow nasal canula. We analyzed 42 consecutive patients with COVID-19 from January 2020 to March 2022. The primary outcomes were the incidence of platypnea-orthodeoxia syndrome, the time with required long-term oxygen therapy, and short-term prognosis. Additionally, we examined the relationships between platypnea-orthodeoxia syndrome and COVID-19 severity, the time with long-term oxygen therapy, and short-term prognosis. Of the 42 included patients, 15 (35.7 %) had platypnea-orthodeoxia syndrome. Although mortality was not significantly different between both groups, the oxygen withdrawal rate in the platypnea-orthodeoxia syndrome group was significantly lower than that in the group without this syndrome. Clinical staff should be aware of the possibility of platypnea-orthodeoxia syndrome during positional changes in patients with COVID-19. Recognizing POS can improve early detection, countermeasures, and safety during physiotherapy.
本回顾性观察研究旨在评估 COVID-19 患者在接受机械通气或高流量鼻导管治疗时出现的 呼吸窘迫-低氧血症 综合征的临床特征。我们分析了 2020 年 1 月至 2022 年 3 月期间的 42 例连续 COVID-19 患者。主要结局是呼吸窘迫-低氧血症 综合征的发生率、需要长期氧疗的时间和短期预后。此外，我们还检查了呼吸窘迫-低氧血症 综合征与 COVID-19 严重程度、长期氧疗时间和短期预后之间的关系。在纳入的 42 例患者中，有 15 例（35.7%）出现呼吸窘迫-低氧血症 综合征。尽管两组之间的死亡率没有显著差异，但呼吸窘迫-低氧血症 综合征组的撤氧率明显低于无该综合征组。临床工作人员应注意 COVID-19 患者体位变化时出现呼吸窘迫-低氧血症 综合征的可能性。识别 POS 可以提高早期检测、对策和物理治疗的安全性。
