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失语症的恢复(第三部分)——多变量分析研究

[Recovery in aphasia (Part 3)--Study by multivariate analysis].

作者信息

Watanabe S, Hojo K, Tasaki H, Hanazono T, Sato T, Metoki H, Oosumi N

出版信息

No To Shinkei. 1987 Feb;39(2):127-33.

PMID:3828147
Abstract

In order to elucidate the factors which have influence on the prognosis of aphasia, correlation between recovery rate of aphasia and the five factors, i.e. initial evaluation of speech test, age, educational level, time between onset and institution of therapy and size of abnormal findings in CT (computed tomography), was studied in 76 right-handed aphasic patients, using multivariate analysis. Cluster analysis and factor analysis were used for analysis of five factors and multiple regression analysis was used for estimation of recovery rate of aphasia. The method of calculation of recovery rate of aphasia is the same to our previous report. The results obtained were as follows: As to analysis of factors, first similarity group among initial evaluation of speech test, recovery rate of aphasia and educational level and second similarity group among time between onset and institution of therapy, size of abnormal findings in CT and age were observed. As to the estimation of recovery rate of aphasia, multiple correlation coefficient of regression analysis using five factors were 0.758, 0.444, 0.627, 0.620, 0.810 and 0.375 respectively in total score, hearing, speaking, reading, writing and calculation on standard language test of aphasia. As to the weight or partial correlation coefficient of regression analysis to the five factors, initial evaluation of speech test, time between onset and institution of therapy and educational level were 129.46, -49.93 and 45.65 respectively and the one of the size of abnormal findings in CT was not high. Stepwise multiple regression analysis of five factors were made.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

为了阐明影响失语症预后的因素,我们对76例右利手失语症患者进行了多因素分析,研究了失语症恢复率与五个因素之间的相关性,这五个因素分别是言语测试的初始评估、年龄、教育水平、发病至开始治疗的时间以及CT(计算机断层扫描)异常发现的大小。采用聚类分析和因子分析对五个因素进行分析,采用多元回归分析估计失语症的恢复率。失语症恢复率的计算方法与我们之前的报告相同。结果如下:在因素分析方面,观察到言语测试初始评估、失语症恢复率和教育水平之间为第一相似组,发病至开始治疗的时间、CT异常发现的大小和年龄之间为第二相似组。在失语症恢复率的估计方面,在失语症标准语言测试的总分、听力、口语、阅读、写作和计算中,使用五个因素进行回归分析的复相关系数分别为0.758、0.444、0.627、0.620、0.810和0.375。在回归分析对五个因素的权重或偏相关系数方面,言语测试初始评估、发病至开始治疗的时间和教育水平分别为129.46、-49.93和45.65,而CT异常发现大小的权重不高。对五个因素进行了逐步多元回归分析。(摘要截取自250字)

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