Menzies-Gow N J, Shurlock T
Department of Clinical Sciences and Services, Royal Veterinary College, Hawkshead Lane, North Mymms, Herts. AL9 7TA. United Kingdom.
West Lane House, Bishopdale, Leyburn, North Yorkshire. DL8 3TG. United Kingdom.
J Equine Vet Sci. 2024 Feb;133:105015. doi: 10.1016/j.jevs.2024.105015. Epub 2024 Jan 27.
Feedstuffs are often recommended to mitigate potential damage from acid associated with equine squamous gastric disease (ESGD). In acidic conditions, pectin alters its structure to one like mucus and binds the stomach mucosa, whilst alfalfa has a strong intrinsic acid buffering capacity. The study aimed to determine whether feeding a commercial beet pulp/alfalfa/oat fibre mix aids ESGD healing and/or prevention of recurrence. Ten adult horses with naturally occurring ESGD were included. All animals were treated with omeprazole as per the attending veterinarian's recommendation and randomly allocated to also be fed a commercial beet pulp/alfalfa/oat fibre mix (1Kg/horse divided into 2 meals/day; n=5) or no additional feed (n=5) for one month. Gastroscopy was then repeated to assess response to therapy. If the ESGD had healed, omeprazole therapy was discontinued, and the commercial feed given to all horses for a further month. Gastroscopy was repeated to determine ESGD recurrence. The mean (±SD) age of the horses was 11.6 (±3.8) years; 4 mares and 6 geldings; various breeds were represented; and the median (range) initial ESGD grade was 2 (2-4). ESGD had healed (grade 0/4) in all animals after one month. After a further month, ESGD had recurred in significantly (p=0.04) more animals that did not receive the commercial feed initially (3/5; 60%; mean [range] ESGD grade 3 [0,4]) compared to those that did (0/5; 0%; mean [range] ESGD grade 0 [0,0]). Thus, the commercial beet pulp/alfalfa/oat fibre mix aided prevention of ESGD recurrence when fed during the healing and prevention phases.
通常建议使用饲料来减轻与马属动物鳞状胃病（ESGD）相关的酸所造成的潜在损害。在酸性条件下，果胶会将其结构改变为类似黏液的结构，并与胃黏膜结合，而苜蓿具有很强的固有酸缓冲能力。该研究旨在确定喂食一种商业甜菜粕/苜蓿/燕麦纤维混合物是否有助于ESGD的愈合和/或预防复发。纳入了10匹患有自然发生的ESGD的成年马。所有动物均按照主治兽医的建议接受奥美拉唑治疗，并随机分配，其中一组还喂食一种商业甜菜粕/苜蓿/燕麦纤维混合物（1千克/匹马，分为每日两餐；n = 5），另一组不额外喂食（n = 5），为期一个月。然后重复进行胃镜检查以评估治疗反应。如果ESGD已经愈合，则停止奥美拉唑治疗，并让所有马匹继续食用商业饲料一个月。再次进行胃镜检查以确定ESGD是否复发。这些马的平均（±标准差）年龄为11.6（±3.8）岁；4匹母马和6匹阉马；涵盖了各种品种；初始ESGD分级的中位数（范围）为2（2 - 4）。一个月后，所有动物的ESGD均已愈合（0/4级）。再过一个月后，与最初接受商业饲料的动物（0/5；0%；平均[范围]ESGD分级0[0,0]）相比，最初未接受商业饲料的动物中ESGD复发的数量显著更多（p = 0.04）（3/5；60%；平均[范围]ESGD分级3[0,4]）。因此，在愈合和预防阶段喂食商业甜菜粕/苜蓿/燕麦纤维混合物有助于预防ESGD复发。
