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毛发皮质醇浓度与马属动物鳞状胃疾病的严重程度呈负相关。

Hair cortisol concentration is inversely related to the severity of equine squamous gastric disease.

机构信息

School of Animal and Veterinary Sciences, The University of Adelaide, Australia.

Department of Animal and Veterinary Bioscience, School of Animal and Veterinary Sciences, The University of Adelaide, Australia.

出版信息

Vet J. 2019 Jul;249:58-59. doi: 10.1016/j.tvjl.2019.05.009. Epub 2019 May 24.

DOI:10.1016/j.tvjl.2019.05.009
PMID:31239166
Abstract

Equine squamous gastric disease (ESGD) is common in horses and many factors, including stress, may play a role in lesion development. Hair cortisol concentration (HCC) provides a measure of medium to long-term stress and therefore, the relationship between HCC and ESGD was examined in this study. Hair samples were collected from 25 horses and gastroscopy was performed to determine the presence and severity of ESGD. Hair cortisol concentrations were lower in horses with ESGD (P = 0.014), and negatively correlated with lesion severity. Mares had lower HCC than geldings (P = 0.031), and a higher prevalence of ESGD, while age had no significant effect. Further studies are required to determine the relevance of the association between HCC and ESGD.

摘要

马的食管性鳞状细胞增生症(ESGD)在马中很常见,许多因素,包括应激,可能在病变发展中起作用。毛发皮质醇浓度(HCC)提供了一种评估中到长期应激的方法,因此,本研究检查了 HCC 与 ESGD 之间的关系。从 25 匹马中采集毛发样本,并进行胃镜检查以确定 ESGD 的存在和严重程度。患有 ESGD 的马的毛发皮质醇浓度较低(P=0.014),并且与病变严重程度呈负相关。母马的 HCC 低于公马(P=0.031),且 ESGD 的患病率更高,而年龄没有显著影响。需要进一步的研究来确定 HCC 与 ESGD 之间的关联的相关性。

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