Larkin D F, Connolly P, Magner J B, Wood A E, Eustace P
Br J Ophthalmol. 1987 Mar;71(3):177-80. doi: 10.1136/bjo.71.3.177.
Intraocular pressure was measured in 24 patients undergoing elective cardiopulmonary bypass surgery. There was a rapid rise when the bypass circulation began, and this was maintained for about 30 minutes. A simultaneous drop in arterial perfusion pressure and packed cell volume occurred. We suggest that marked haemodilution is responsible for this effect, through increased ocular blood flow and low colloidal osmotic pressure. The possible aetiological significance in relation to ischaemic optic neuropathy complicating cardiopulmonary bypass is discussed.
对24例接受择期体外循环手术的患者测量了眼压。体外循环开始时眼压迅速升高,并持续约30分钟。同时动脉灌注压和红细胞压积下降。我们认为,显著的血液稀释是造成这种影响的原因,这是通过增加眼血流量和降低胶体渗透压实现的。本文讨论了其与体外循环并发缺血性视神经病变可能的病因学意义。