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类风湿关节炎患者中微小单胞菌引起的厌氧性脊椎间盘炎:病例报告及文献复习

Anaerobic Spondylodiscitis caused by Parvimonas Micra in a Rheumatoid Arthritis Patient: Case Report and Review of the Literature.

作者信息

Kalmoukos Panagiotis, Kouroupis Dimitrios, Sapouridis Georgios, Simoulidou Elisavet, Varouktsi Anna, Zarras Charalampos, Petidis Konstantinos, Pyrpasopoulou Athina

机构信息

2 Propaedeutic Department of Internal Medicine.

Department of Radiology.

出版信息

Mediterr J Rheumatol. 2023 Aug 24;34(4):525-530. doi: 10.31138/mjr.240823.asc. eCollection 2023 Dec.

DOI:10.31138/mjr.240823.asc
PMID:38282925
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10815523/
Abstract

We report the rare case of bacteraemia and secondary spondylodiscitis probably triggered by tooth injury in a rheumatoid arthritis patient. Anaerobic bacteria associated spondylodiscitis may evade diagnosis due to atypical clinical presentation usually lacking fever, and the difficulties related to microbiological characterisation of the pathogen. Even though anaerobic spinal infections may constitute <3% of the total, clinical suspicion should remain high, especially in the case of positive history for pre-existing oral cavity or gastrointestinal/gynaecological tract infections.

摘要

我们报告了一例罕见病例,一名类风湿性关节炎患者因牙齿损伤引发菌血症和继发性脊椎椎间盘炎。与厌氧细菌相关的脊椎椎间盘炎可能因通常无发热的非典型临床表现以及病原体微生物特征鉴定的困难而漏诊。尽管厌氧性脊柱感染可能占总数的不到3%,但临床怀疑仍应高度警惕,尤其是在有口腔或胃肠道/生殖道既往感染阳性史的情况下。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb1/10815523/6e4000e1363e/MJR-34-4-525-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb1/10815523/6e4000e1363e/MJR-34-4-525-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4bb1/10815523/6e4000e1363e/MJR-34-4-525-g001.jpg

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本文引用的文献

1
Spondylodiscitis in Geriatric Patients: What Are the Issues?老年患者的脊椎椎间盘炎:问题有哪些?
Global Spine J. 2023 Apr;13(1_suppl):73S-84S. doi: 10.1177/21925682221121300.
2
Management of vertebral osteomyelitis in adults.成人脊椎骨髓炎的管理
Br J Hosp Med (Lond). 2023 Jan 2;84(1):1-5. doi: 10.12968/hmed.2022.0362. Epub 2023 Jan 16.
3
Infection Route of : A Case Report and Systematic Review.感染途径:病例报告与系统评价
Healthcare (Basel). 2022 Sep 8;10(9):1727. doi: 10.3390/healthcare10091727.
4
Anaerobic spondylodiscitis: a retrospective analysis.厌氧性脊椎骨髓炎:回顾性分析。
BMC Musculoskelet Disord. 2022 Aug 17;23(1):788. doi: 10.1186/s12891-022-05749-0.
5
Large increase of vertebral osteomyelitis in France: a 2010-2019 cross-sectional study.法国椎骨骨髓炎的大量增加:2010-2019 年的横断面研究。
Epidemiol Infect. 2021 Oct 6;149:e227. doi: 10.1017/S0950268821002181.
6
Imaging update on musculoskeletal infections.肌肉骨骼感染的影像学进展
J Clin Orthop Trauma. 2021 Sep 16;22:101600. doi: 10.1016/j.jcot.2021.101600. eCollection 2021 Nov.
7
Clinical characteristics of pyogenic vertebral osteomyelitis, and factors associated with inadequate treatment response.化脓性脊柱骨髓炎的临床特征,以及与治疗反应不足相关的因素。
Int J Infect Dis. 2021 Jul;108:487-493. doi: 10.1016/j.ijid.2021.05.078. Epub 2021 Jun 4.
8
Clinical characteristics of bloodstream infection by Parvimonas micra: retrospective case series and literature review.微小消化链球菌血流感染的临床特征:回顾性病例系列和文献复习。
BMC Infect Dis. 2020 Aug 5;20(1):578. doi: 10.1186/s12879-020-05305-y.
9
Parvimonas micra as a rare cause of spondylodiscitis - case series from a single centre.微小单胞菌作为脊椎椎间盘炎的罕见病因——单中心病例系列研究。
Swiss Med Wkly. 2020 Jun 16;150:w20272. doi: 10.4414/smw.2020.20272. eCollection 2020 Jun 15.
10
Microbial Etiology of Pyogenic Vertebral Osteomyelitis According to Patient Characteristics.根据患者特征分析化脓性脊椎骨髓炎的微生物病因
Open Forum Infect Dis. 2020 May 20;7(6):ofaa176. doi: 10.1093/ofid/ofaa176. eCollection 2020 Jun.