Weber G
Biochemistry. 1987 Jan 13;26(1):331-2. doi: 10.1021/bi00375a046.
The calculations presented in a recent paper [Johnson, M. L. (1986) Biochemistry 25, 791-797] to the effect that the free energy couplings between oxygen binding and subunit association in hemoglobin A can be of either first or second order are examined. The fitting of the experimental data to a system with second-order couplings carried out by Johnson belongs to a tetramer in which, in contradistinction to hemoglobin A, oxygen binding promotes subunit association.
一篇近期论文[约翰逊，M. L.（1986年）《生物化学》25卷，791 - 797页]提出，血红蛋白A中氧结合与亚基缔合之间的自由能耦合可以是一级或二级的，本文对此进行了研究。约翰逊将实验数据拟合到具有二级耦合的系统，该系统属于一种四聚体，与血红蛋白A不同的是，在这种四聚体中氧结合促进亚基缔合。
