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WS 掺杂 ZnO 纳米颗粒的结构与抗菌性能研究

Investigation of Structural and Antibacterial Properties of WS-Doped ZnO Nanoparticles.

作者信息

Beytür Sercan, Essiz Sebnem, Özuğur Uysal Bengü

机构信息

Faculty of Engineering and Natural Sciences, Kadir Has University, Cibali, Fatih, Istanbul 34083, Turkey.

出版信息

ACS Omega. 2024 Jan 5;9(3):4037-4049. doi: 10.1021/acsomega.3c09041. eCollection 2024 Jan 23.

Abstract

ZnO nanoparticles, well-known for their structural, optical, and antibacterial properties, are widely applied in diverse fields. The doping of different materials to ZnO, such as metals or metal oxides, is known to ameliorate its properties. Here, nanofilms composed of ZnO doped with WS at 5, 15, and 25% ratios are synthesized, and their properties are investigated. Supported by molecular docking analyses, the enhancement of the bactericidal properties after the addition of WS at different ratios is highlighted and supported by the inhibitory interaction of residues playing a crucial role in the bacterial survival through the targeting of proteins of interest.

摘要

氧化锌纳米颗粒以其结构、光学和抗菌性能而闻名,被广泛应用于各种领域。众所周知,向氧化锌中掺杂不同的材料,如金属或金属氧化物,可以改善其性能。在此,合成了分别以5%、15%和25%的比例掺杂WS的氧化锌纳米薄膜,并对其性能进行了研究。在分子对接分析的支持下,突出显示了在添加不同比例的WS后杀菌性能的增强,并且通过靶向感兴趣的蛋白质,对在细菌存活中起关键作用的残基的抑制性相互作用也支持了这一点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71dd/10809239/8345a84de93c/ao3c09041_0001.jpg

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