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使用Impella支持治疗急性主动脉夹层伴左冠状动脉灌注不良的术前管理:一例报告

Preoperative management using Impella support for acute aortic dissection with left coronary malperfusion: a case report.

作者信息

Shojima Takahiro, Takagi Kazuyoshi, Saku Kosuke, Fukuda Tomofumi, Tayama Eiki

机构信息

Division of Cardiovascular Surgery, Department of Surgery, Kurume University School of Medicine, 67 Asahimachi, Kurume, Fukuoka, 830-0011, Japan.

出版信息

Egypt Heart J. 2024 Jan 29;76(1):11. doi: 10.1186/s43044-024-00439-9.

Abstract

BACKGROUND

Acute aortic dissection (AAD) with impaired perfusion of the left coronary artery has a poor prognosis, even after urgent radical aortic surgery, due to extensive myocardial damage. Although Impella, a microaxial-flow catheter pump, is useful in managing acute myocardial infarction, it is generally contraindicated in patients with AAD because it is an intra-aortic device and the aortic structure is compromised in these cases. Here, we introduce a novel intervention that allowed a planned aortic repair after managing circulation using Impella and venoarterial extracorporeal membrane oxygenation in a case of AAD with left main trunk malperfusion.

CASE PRESENTATION

A 40-year-old man presented with cardiogenic shock. Percutaneous coronary intervention was performed to address left main trunk obstruction using an intra-aortic balloon pump; however, circulatory instability persisted. The patient was transferred to our hospital after venoarterial extracorporeal membrane oxygenation. Impella CP™ was used to improve his circulatory status. However, a subsequent CT scan confirmed an AAD diagnosis. After 5 days of stable circulatory support, the patient underwent aortic root replacement and coronary artery bypass grafting.

CONCLUSIONS

In patients with AAD and coronary malperfusion, adjunctive circulatory management with Impella may be a valuable therapeutic option.

摘要

背景

急性主动脉夹层(AAD)合并左冠状动脉灌注受损预后较差,即便进行了紧急主动脉根治手术,由于广泛的心肌损伤,预后依然不佳。尽管微轴流导管泵Impella在急性心肌梗死的治疗中很有用,但在AAD患者中通常是禁忌的,因为它是一种主动脉内装置,而在这些病例中主动脉结构已受损。在此,我们介绍一种新的干预措施,在一例左主干灌注不良的AAD病例中,使用Impella和静脉-动脉体外膜肺氧合(ECMO)进行循环管理后,成功进行了计划性主动脉修复。

病例介绍

一名40岁男性因心源性休克入院。使用主动脉内球囊泵进行经皮冠状动脉介入治疗以解决左主干阻塞问题;然而,循环不稳定持续存在。在接受静脉-动脉体外膜肺氧合后,患者被转至我院。使用Impella CP™改善其循环状态。然而,随后的CT扫描确诊为AAD。在稳定的循环支持5天后,患者接受了主动脉根部置换和冠状动脉搭桥术。

结论

对于患有AAD和冠状动脉灌注不良的患者,使用Impella进行辅助循环管理可能是一种有价值的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b9e4/10825086/fdceea9a0276/43044_2024_439_Fig1_HTML.jpg

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