Favaretto A L, Lamano-Carvalho T L, Ferreira A L, Antunes-Rodrigues J
Braz J Med Biol Res. 1986;19(2):233-9.
We evaluated the effect of testicular denervation on the spermatogenetic and secretory activities of the adult rat testis. Testes were denervated by applying 20% (v/v) phenol to the spermatic cord and measurements were made 30 days thereafter. There was an increase in the frequency of stages VII-VIII of the seminiferous epithelium cycle, indicating an increase in the relative amount of mature elongated spermatids present in the seminiferous tubules. The frequency of stage XIV remained unchanged, suggesting that the rate of reductional divisions was constant. A decrease in the nuclear volume of Leydig cells paralleled increased plasma LH and testosterone levels. The results are discussed in terms of a possible role of phenol-sensitive neural elements which affect testicular spermatogenetic and secretory functions.
我们评估了睾丸去神经支配对成年大鼠睾丸生精和分泌活动的影响。通过向精索涂抹20%（v/v）苯酚使睾丸去神经支配，30天后进行测量。生精上皮周期VII - VIII期的频率增加，表明生精小管中成熟延长型精子细胞的相对数量增加。XIV期的频率保持不变，表明减数分裂的速率恒定。睾丸间质细胞的核体积减小，同时血浆促黄体生成素（LH）和睾酮水平升高。根据影响睾丸生精和分泌功能的酚敏感神经元件的可能作用对结果进行了讨论。
