Carvalho T L, Favaretto A L, Rodrigues J A, Ferreira A L
Anat Anz. 1985;159(1-5):33-41.
A study was carried out to evaluate the effect of testicular denervation on the spermatogenetic activity of the testes and on the ability of the germinal epithelium to respond to chronic administration of hCG. Testes of adult rats were denervated by phenolization of the spermatic cord. An increase in the frequency of stages VII-VIII of the tubular cycle was observed 30 d later in phenolized rats treated with hCG, demonstrating an increase in the amount of spermatozoa present in the seminiferous tubules of these animals. The frequency of stage XIV remained unchanged after phenolization of the spermatic cord and/or chronic treatment with hCG, indicating that the rate of reductional divisions remained constant. The results suggest the autonomic nervous system may have some functional significance by participating in a neuroendocrine mechanism and consequently in the spermatogenesis.
开展了一项研究,以评估睾丸去神经支配对睾丸生精活性以及生精上皮对慢性给予人绒毛膜促性腺激素(hCG)反应能力的影响。通过精索酚化对成年大鼠的睾丸进行去神经支配。30天后,在接受hCG治疗的酚化大鼠中观察到生精小管周期VII - VIII期的频率增加,表明这些动物的生精小管中存在的精子数量增加。精索酚化和/或hCG慢性治疗后,XIV期的频率保持不变,这表明减数分裂的速率保持恒定。结果表明,自主神经系统可能通过参与神经内分泌机制并因此参与精子发生而具有一定的功能意义。