Global Health Research Center, Duke Kunshan University, Kunshan, Jiangsu, China.
Department of Biostatistics and Epidemiology, School of Public Health, China Medical University, Shenyang, Liaoning, China.
Eur J Public Health. 2024 Apr 3;34(2):218-224. doi: 10.1093/eurpub/ckae003.
Among people living with frailty, adherence to a healthy lifestyle may be a low-cost and effective strategy to decrease frailty-induced health risks across different social environments.
We included 15 594 frail participants at baseline from the UK Biobank study. We used four lifestyle factors to create a composite healthy lifestyle score and 17 social factors to construct a polysocial score. We classified the lifestyle score into two levels (unhealthy and healthy) and the polysocial score into three levels (low, intermediate and high). We used Cox regression to determine the association of each lifestyle factor and lifestyle score with all-cause mortality, respectively. We also examined the associations across polysocial score categories. We evaluated the joint association of the lifestyle score and the categorical polysocial score with all-cause mortality.
During up to 14.41 follow-up years, we documented 3098 all-cause deaths. After multivariable adjustment, we found a significant association between not smoking and adequate physical activity with all-cause mortality across polysocial score categories, respectively. We also found a significant association between a healthy diet and all-cause mortality among frail participants living in an intermediate social environment. A healthy lifestyle was associated with a lower all-cause mortality risk across polysocial score categories, especially among those with a low polysocial score.
Adherence to a healthy lifestyle, particularly not smoking, adequate physical activity and a healthy diet, may provide a feasible solution to decreasing mortality risk among frail adults across different social environments, especially for those in the socially disadvantaged group.
在衰弱的人群中，坚持健康的生活方式可能是一种低成本且有效的策略，可以降低不同社会环境下衰弱引起的健康风险。
我们从英国生物库研究中纳入了 15594 名基线时虚弱的参与者。我们使用四个生活方式因素来创建一个综合健康生活方式评分，并使用 17 个社会因素来构建一个多社会评分。我们将生活方式评分分为两个水平（不健康和健康），将多社会评分分为三个水平（低、中、高）。我们使用 Cox 回归来确定每个生活方式因素和生活方式评分与全因死亡率的关联。我们还检查了多社会评分类别之间的关联。我们评估了生活方式评分和分类多社会评分与全因死亡率的联合关联。
在长达 14.41 年的随访期间，我们记录了 3098 例全因死亡。经过多变量调整后，我们发现不吸烟和适度的体力活动与多社会评分类别中的全因死亡率之间存在显著关联。我们还发现，在处于中等社会环境的衰弱参与者中，健康饮食与全因死亡率之间存在显著关联。健康的生活方式与多社会评分类别中的全因死亡率降低风险相关，尤其是在社会劣势群体中。
坚持健康的生活方式，特别是不吸烟、适度的体力活动和健康的饮食，可能为降低不同社会环境中衰弱成年人的死亡率风险提供可行的解决方案，尤其是对那些处于社会劣势群体的人。
