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监狱中阿片类药物维持治疗方案治疗药物依赖的效果。

Effectiveness of opioid maintenance programs for treating drug dependence in prisons.

机构信息

Universitat Jaume I. Castelló. Spain.

出版信息

Rev Esp Sanid Penit. 2023 Sep-Dec;25(3):112-121. doi: 10.18176/resp.00077.

DOI:10.18176/resp.00077
PMID:38289166
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10910325/
Abstract

OBJECTIVES

To evaluate the effectiveness of opioid maintenance programs in treating opioid dependence in Spanish prisons.

MATERIAL AND METHOD

A narrative bibliographic review was carried out on the following databases: PubMed; Cochrane; IBECS; LILACS; HealthCare. All clinical trials were chosen as a preference, along with systematic review articles and some articles that were considered relevant for their content. The time period was limited to between January 2011 and November 2021. The languages chosen were English, Spanish and Catalan. Repeated articles and those that were not related to the objectives were rejected. The search criteria were: "methadone AND prisons"; "opiate substitution treatment AND prisons"; "methadone AND buprenorphine"; "methadone OR buprenorphine"; "prisons AND Methadone AND buprenorphine".

RESULTS

20 articles were selected out of 647 items consulted after applying the corresponding filters and after discarding duplicates.

DISCUSSION

There was a slightly greater effectiveness of buprenorphine versus methadone. The high prevalence of the program was highlighted, as well as the variety of adverse effects of methadone. Usefulness with regard to inmates' behavior showed a range of opinions. The possibility of new treatment alternatives with better pharmacological control is mentioned.

摘要

目的

评估阿片类药物维持治疗方案在西班牙监狱中治疗阿片类药物依赖的效果。

材料和方法

对以下数据库进行了叙述性文献综述:PubMed;Cochrane;IBECS;LILACS;HealthCare。选择了所有临床试验,以及系统评价文章和一些被认为与内容相关的文章。时间范围限于 2011 年 1 月至 2021 年 11 月。选择的语言为英语、西班牙语和加泰罗尼亚语。重复的文章和与目标不相关的文章被拒绝。搜索标准为:“美沙酮和监狱”;“阿片类药物替代治疗和监狱”;“美沙酮和丁丙诺啡”;“美沙酮或丁丙诺啡”;“监狱和美沙酮和丁丙诺啡”。

结果

在应用相应的过滤器并排除重复项后,从 647 项咨询中选择了 20 篇文章。

讨论

丁丙诺啡相对于美沙酮的效果略好。方案的高流行率以及美沙酮的各种不良反应得到了强调。关于囚犯行为的有用性显示出各种意见。提到了具有更好药理控制的新治疗替代方案的可能性。

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本文引用的文献

1
Underrepresentation of diverse populations and clinical characterization in opioid agonist treatment research: A systematic review of the neurocognitive effects of buprenorphine and methadone treatment.阿片类激动剂治疗研究中不同人群的代表性不足及临床特征:丁丙诺啡和美沙酮治疗神经认知效应的系统评价
J Subst Abuse Treat. 2022 Apr;135:108644. doi: 10.1016/j.jsat.2021.108644. Epub 2021 Oct 23.
2
Recent advances in the treatment of opioid use disorders-focus on long-acting buprenorphine formulations.阿片类物质使用障碍治疗的最新进展——聚焦于长效丁丙诺啡制剂
World J Psychiatry. 2021 Sep 19;11(9):543-552. doi: 10.5498/wjp.v11.i9.543.
3
Prolonged-release buprenorphine formulations: Perspectives for clinical practice.
长效丁丙诺啡制剂:临床实践的视角。
Therapie. 2020 Sep-Oct;75(5):397-406. doi: 10.1016/j.therap.2020.05.007. Epub 2020 May 18.
4
What place for prolonged-release buprenorphine depot-formulation Buvidal® in the treatment arsenal of opioid dependence? Insights from the French experience on buprenorphine.布地奈德缓释剂 Buvidal® 在阿片类药物依赖治疗武器库中占有什么地位?布比卡因在法国的经验洞察。
Expert Opin Drug Deliv. 2019 Sep;16(9):907-914. doi: 10.1080/17425247.2019.1649252. Epub 2019 Aug 23.
5
Initiating methadone in jail and in the community: Patient differences and implications of methadone treatment for reducing arrests.在监狱和社区中启动美沙酮治疗:患者差异以及美沙酮治疗减少逮捕的影响。
J Subst Abuse Treat. 2019 Feb;97:7-13. doi: 10.1016/j.jsat.2018.11.006. Epub 2018 Nov 19.
6
Pharmacotherapy for opioid addiction in community corrections.社区矫正中的阿片类药物成瘾的药物治疗。
Int Rev Psychiatry. 2018 Oct;30(5):117-135. doi: 10.1080/09540261.2018.1524373. Epub 2018 Dec 6.
7
Methadone and the QTc Interval: Paucity of Clinically Significant Factors in a Retrospective Cohort.美沙酮与 QT 间期:回顾性队列研究中临床意义不大的因素。
J Addict Med. 2017 Nov/Dec;11(6):489-493. doi: 10.1097/ADM.0000000000000353.
8
Pharmacotherapy of Opioid Addiction: "Putting a Real Face on a False Demon".阿片类药物成瘾的药物治疗:“让虚假恶魔现出真面目”
J Med Toxicol. 2016 Mar;12(1):58-63. doi: 10.1007/s13181-015-0517-5.
9
Pharmacological interventions for drug-using offenders.针对吸毒罪犯的药物干预措施。
Cochrane Database Syst Rev. 2015 Jun 2;2015(6):CD010862. doi: 10.1002/14651858.CD010862.pub2.
10
[Is the availability of buprenorphine/naloxone therapy for opioid-dependent inmates a necessity? ].[丁丙诺啡/纳洛酮疗法用于阿片类药物依赖囚犯是否有必要?]
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