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在一家三级医疗中心的泌尿科接受根治性膀胱切除术治疗膀胱癌的患者中的前列腺癌。

Prostate Cancer among Patients Undergoing Radical Cystoprostatectomy for Bladder Cancer in the Department of Urology in a Tertiary Care Centre.

机构信息

Department of Urology, The Second Affiliated Hospital of Kunming Medical University, Yunnan Institute of Urology, Kunming, Yunnan, People's Republic of China.

出版信息

JNMA J Nepal Med Assoc. 2023 Oct 1;61(266):782-786. doi: 10.31729/jnma.8309.

Abstract

INTRODUCTION

Prostate cancer is the most common malignancy in men and remains one of the most prevalent and least understood of all human malignancies. Bladder cancer is the most frequently diagnosed cancer in China. Radical cystectomy remains the gold standard for muscle-invasive, recurrent and multiple bladder cancer. All male patients undergoing radical cystoprostatectomy must be evaluated for prostate cancer before planning surgery. The aim of this study was to find out the prevalence of prostate cancer among patients undergoing radical cystoprostatectomy undergoing surgery for bladder cancer.

METHODS

A descriptive cross-sectional study was conducted in a tertiary care centre from 1 August 2023 to 30 August 2023 where data from 1 January 2015 to 30 December 2017 was taken from medical records after obtaining ethical approval from the Ethical Review Board. All patients who underwent radical cystoprostatectomy were included in the study. Whole radical cystoprostatectomy specimens were cut transversely at 3 mm intervals and examined in the same pathological centre. Clinically significant prostate cancer was defined as a tumour with a Gleason pattern ≥4, prostate tumour with clinical stage ≥pT3, lymph node. involvement, positive surgical margin or multifocality of three or more lesions. A convenience sampling method was used. The point estimate was calculated at a 95% Confidence Interval.

RESULTS

Among 210 patients, 52 (24.76%) (18.92-30.60, 95% Confidence Interval) had incidental prostate cancer. The average age of patients with incidental prostate cancer was 65.88±9.54 years.

CONCLUSIONS

The prevalence of incidental prostate cancer was found to be lower than the study conducted in a similar setting.

KEYWORDS

bladder cancer; incidental findings; prostate cancer.

摘要

介绍

前列腺癌是男性最常见的恶性肿瘤,也是所有人类恶性肿瘤中最常见但了解最少的一种。膀胱癌是中国最常见的癌症。根治性膀胱切除术仍然是肌层浸润性、复发性和多发性膀胱癌的金标准。所有接受根治性膀胱前列腺切除术的男性患者在计划手术前都必须评估前列腺癌。本研究旨在了解膀胱癌患者接受根治性膀胱前列腺切除术后前列腺癌的患病率。

方法

本研究是在一家三级保健中心进行的描述性横断面研究,研究时间为 2023 年 8 月 1 日至 2023 年 8 月 30 日,数据来自 2015 年 1 月 1 日至 2017 年 12 月 30 日的病历,在获得伦理审查委员会的伦理批准后。所有接受根治性膀胱前列腺切除术的患者均纳入本研究。整个根治性膀胱前列腺切除术标本以 3mm 的间隔横向切开,并在同一病理中心进行检查。临床显著前列腺癌定义为肿瘤具有 Gleason 模式≥4、临床分期≥pT3、淋巴结受累、阳性手术切缘或 3 个或更多病变的多灶性。采用方便抽样法。点估计值在 95%置信区间内计算。

结果

在 210 名患者中,52 名(24.76%)(95%置信区间为 18.92-30.60)患有偶然前列腺癌。偶然前列腺癌患者的平均年龄为 65.88±9.54 岁。

结论

偶然前列腺癌的患病率低于在类似环境中进行的研究。

关键词

膀胱癌;偶然发现;前列腺癌。

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