Department of Clinical and Preventive Nutrition Sciences, School of Health Professions, Rutgers, University, Newark, New Jersey, USA.
Nutr Clin Pract. 2024 Aug;39(4):824-836. doi: 10.1002/ncp.11117. Epub 2024 Jan 30.
Cow's milk elimination (CME) is an established treatment, similar to other forms of diet therapy, for eosinophilic esophagitis (EoE). However, there is limited research to support its efficacy as a primary treatment. This review evaluated studies published in the past 10 years that assessed the outcomes after CME on histologic remission, clinical findings, and quality of life (QoL) in children aged 2-18 years with EoE. The evidence demonstrated that CME was effective at achieving histologic remission of disease in 50%-65% of children. This intervention also improved clinical symptoms seen on endoscopy and resulted in increased QoL when self-reported by children. CME can be used as a primary treatment for some children with EoE.
牛奶剔除(CME)是一种已确立的治疗方法,类似于其他形式的饮食疗法,用于治疗嗜酸性食管炎(EoE)。然而,支持其作为主要治疗方法的疗效的研究有限。本综述评估了过去 10 年中发表的评估 CME 对 2-18 岁 EoE 儿童组织学缓解、临床发现和生活质量(QoL)影响的研究。证据表明,CME 可有效使 50%-65%的儿童达到疾病的组织学缓解。这种干预措施还改善了内镜下观察到的临床症状,并使儿童自我报告的生活质量得到提高。CME 可用于某些 EoE 儿童的主要治疗。