Neves Sara, Pos Ema, Horta Ana, Vasconcelos António Ludgero
Infectious Diseases Department, Centro Hospitalar Universitário de Santo António, Porto, PRT.
Cureus. 2023 Dec 31;15(12):e51388. doi: 10.7759/cureus.51388. eCollection 2023 Dec.
is a slow-growing nontuberculous mycobacterium (NTM). It was first described in 1972 and is responsible for less than 0.2% of all NTM infections. The most common presentation resembles pulmonary tuberculosis, but it may also present as an extrapulmonary disease. It primarily affects individuals with underlying lung disease or immunocompromising conditions. The increasing use of tumor necrosis factor-alpha inhibitors, such as adalimumab, is associated with an increased risk of serious infections. We report a case of infection in a 23-year-old woman with a history of childhood pneumonia and Crohn's disease on adalimumab.
是一种生长缓慢的非结核分枝杆菌(NTM)。它于1972年首次被描述,在所有NTM感染中所占比例不到0.2%。最常见的表现类似于肺结核,但也可能表现为肺外疾病。它主要影响有潜在肺部疾病或免疫功能低下状况的个体。肿瘤坏死因子-α抑制剂(如阿达木单抗)的使用增加与严重感染风险增加有关。我们报告一例23岁女性感染病例,该女性有儿童期肺炎病史,正在使用阿达木单抗治疗克罗恩病。