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加纳博诺、博诺东部和阿哈福地区精神药物多药联用的患病率及开方者的知晓情况

Prevalence and prescribers' knowledge of psychotropic polypharmacy in the Bono, Bono East, and Ahafo Regions, Ghana.

作者信息

Dumba James, Barimah Antwi Joseph, Ibrahim Mohammed Mohammed, Allotey Solomon Saka, Alorvi Semefa, Appertey William, Sopaal Luke, Acheampong Frank, Commey Rebecca Dorcas, Boakye Nketiah Yaw, Ampofo Deborah, Amoah Bernard Opoku, Agyemang Larry

机构信息

College of Health Yamfo, Ghana.

出版信息

Heliyon. 2024 Jan 8;10(2):e24243. doi: 10.1016/j.heliyon.2024.e24243. eCollection 2024 Jan 30.

DOI:10.1016/j.heliyon.2024.e24243
PMID:38293502
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10825345/
Abstract

The use of psychotropic medications for treating simple and complex psychological and emotional problems is common and relevant among prescribers. This, therefore, come with the tendency to prescribe many medications to a patient on a single visit due to varied reasons. The study, therefore, sought to ascertain the prevalence and prescribers' knowledge of psychotropic polypharmacy. A quantitative, descriptive study was conducted using a simple random approach to select and review the prescription records (both regular and prn basis) of three hundred and nine (309) patients' folders retrospectively within seven (7) mental health units across the study area to ascertain the prevalence of Psychotropic Polypharmacy (PP). Fifty-eight (58) prescribers were selected using probability method (simple random) to respond to the study questionnaire. Psychotropic Polypharmacy was prevalent (66.0 %) in the study area with antipsychotic polypharmacy (74.0 %) being the common form with the co-prescription of chlorpromazine (CPZ) + haloperidol (70.0 %) being frequent. This was more predominant among male patients (78.0 %) than female patients (22.0 %). Prescribers had high (82.8 %) knowledge of Psychotropic Polypharmacy and the majority (68.9 %) disagreed that the practice of Psychotropic Polypharmacy should be promoted. The continuous training of prescribers (i.e. mental health officers) on rational prescriptions would help reduce the prevalence of Psychotropic Polypharmacy.

摘要

在开处方者中,使用精神药物治疗简单和复杂的心理及情绪问题很常见且具有相关性。因此,由于各种原因,在一次就诊时给患者开多种药物的情况时有发生。所以,该研究旨在确定精神药物多药联用的患病率以及开处方者对其的了解程度。采用简单随机抽样方法进行了一项定量描述性研究,回顾性选取并审查了研究区域内七个精神卫生单位的309份患者病历(包括常规和按需用药记录),以确定精神药物多药联用(PP)的患病率。使用概率抽样方法(简单随机抽样)选取了58名开处方者来回答研究问卷。精神药物多药联用在研究区域较为普遍(66.0%),其中抗精神病药物多药联用(74.0%)最为常见,氯丙嗪(CPZ)+氟哌啶醇的联合处方(70.0%)较为频繁。这在男性患者中(78.0%)比女性患者中(22.0%)更为突出。开处方者对精神药物多药联用有较高的了解程度(82.8%),且大多数(68.9%)不同意应推广精神药物多药联用的做法。对开处方者(即精神卫生官员)进行合理处方的持续培训将有助于降低精神药物多药联用的患病率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/0d89d237112d/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/98f5d32ddbb0/gr1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/0fd3789177ff/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/0d89d237112d/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/98f5d32ddbb0/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/c02a54200305/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/1c9cf896e8da/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/0fd3789177ff/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/60aa/10825345/0d89d237112d/gr5.jpg

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本文引用的文献

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Polypharmacy Is Associated with Lower Memory Function in African American Older Adults.
多重用药与非裔美国老年人较低的记忆功能有关。
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Polypharmacy Associated with Cognitive Decline in Newly Diagnosed Parkinson's Disease: A Cross-Sectional Study.新诊断帕金森病中与认知功能减退相关的多重用药:一项横断面研究
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Physician Care Coordination and the Use of Psychotropic Polypharmacy in the Management of Pediatric Mental Disorders.医师医疗协调与精神科药物的广泛使用在儿科精神障碍管理中的应用。
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