Zarean Elham, Samani Zahra Bahrami, Kheiri Soleiman, Torkian Samaneh
Department of Psychiatry, School of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Clinical Research Development Unit, Hajar Hospital, Shahrekord University of Medical Sciences, Shahrekord, Iran.
Front Psychiatry. 2024 Jan 16;14:1302715. doi: 10.3389/fpsyt.2023.1302715. eCollection 2023.
Psychological factors are often overlooked as potential contributors to cardiovascular disease. This study aimed to investigate the relationship between depression, anxiety, and quality of life with chest pain origin.
This cross-sectional study was performed from 2019 to 2020 and included participants from multiple medical centers across Shahrekord, Iran. Participants were recruited through advertisements in medical centers. Participants were divided into three groups: healthy control ( = 67), chest pain with cardiac origin (CCP) ( = 70), and chest pain with non-cardiac origin (NCCP) ( = 73). Data were collected using the Beck's Anxiety scale, Beck's Depression scale, and Short-Form Health Survey questionnaires. The chi-square, exact test, -test, Kruskal-Wallis, and logistic regression models were used for statistical analysis. All analysis was performed using SPSS 26.
The mean scores of depression and anxiety in the NCCP group (depression = 17.03 ± 11.93, anxiety = 17.18 ± 11.37) were significantly higher than those in the CCP (depression = 9.73 ± 5.76, anxiety = 8.77 ± 5.96) and healthy (depression = 7.00 ± 7.61, anxiety = 6.18 ± 7.63) groups ( < 0.05). The mean score of quality of life in the NCCP group (54.87 ± 12.66) was significantly lower than that in the CCP (76.31 ± 12.49) and healthy (80.94 ± 15.78) groups ( < 0.05). Patients with NCCP had higher odds of having depression (adjusted OR = 4.39, 95% CI: 1.25, 15.35) and lower odds for having mental quality of life scores than the CCP and health groups, respectively (adjusted OR = 0.90, 95% CI: 0.87, 0.94).
Our findings suggest that collaboration between psychiatrists and other specialists may be necessary to improve patients' health conditions and quality of life.
心理因素常被忽视，未被视作心血管疾病的潜在促成因素。本研究旨在调查抑郁、焦虑和生活质量与胸痛病因之间的关系。
本横断面研究于2019年至2020年开展，纳入了伊朗设拉子多个医疗中心的参与者。参与者通过医疗中心的广告招募。参与者被分为三组：健康对照组（n = 67）、心脏源性胸痛（CCP）组（n = 70）和非心脏源性胸痛（NCCP）组（n = 73）。使用贝克焦虑量表、贝克抑郁量表和简短健康调查问卷收集数据。采用卡方检验、确切概率检验、t检验、Kruskal-Wallis检验和逻辑回归模型进行统计分析。所有分析均使用SPSS 26完成。
NCCP组的抑郁和焦虑平均得分（抑郁 = 17.03 ± 11.93，焦虑 = 17.18 ± 11.37）显著高于CCP组（抑郁 = 9.73 ± 5.76，焦虑 = 8.77 ± 5.96）和健康组（抑郁 = 7.00 ± 7.61，焦虑 = 6.18 ± 7.63）（P < 0.05）。NCCP组的生活质量平均得分（54.87 ± 12.66）显著低于CCP组（76.31 ± 12.49）和健康组（80.94 ± 15.78）（P < 0.05）。与CCP组和健康组相比，NCCP组患者患抑郁症的几率更高（调整后OR = 4.39，95% CI：1.25，15.35），心理健康生活质量得分的几率更低（调整后OR = 0.90，95% CI：0.87，0.94）。
我们的研究结果表明，精神科医生与其他专科医生之间的合作可能对于改善患者健康状况和生活质量是必要的。
