Department of Medicine, University of Hong Kong, Hong Kong.
J Clin Gastroenterol. 2009 Jan;43(1):13-8. doi: 10.1097/MCG.0b013e3181514725.
Chest pain is common and data regarding noncardiac chest pain (NCCP) in Asia are lacking.
To determine the differences in clinical presentations, psychologic impact, and quality of life between patients with NCCP and cardiac chest pain (CCP), and to identify any factors that impacted on these patients.
Consecutive patients undergoing coronary angiography for the evaluation of chest pain were recruited in Hong Kong and Wuhan, China. One hundred and forty patients with abnormal and 141 patients with normal angiography were included in the study. The validated gastroesophageal reflux disease questionnaire, the Hospital Anxiety-Depression Scale, and the 12-item Short Form Health Survey (SF-12) were used for assessment.
NCCP patients reported similar days-off work and impairment of their social life compared with those with CCP. No difference was found in the anxiety and depression scores between the 2 groups. NCCP patients with reflux symptoms had higher anxiety score (7.19 vs. 5.74, P=0.044), reported more interruption of their social life (26% vs. 5%, P<0.0001), and had taken more sick leaves (17% vs. 5%, P=0.018) compared with those without gastroesophageal reflux disease.
The quality of life and psychologic impact of patients with NCCP were as significant as those with CCP. NCCP patients with reflux symptoms were more anxious and were impaired in their productivity and social life.
胸痛很常见，亚洲缺乏非心源性胸痛（NCCP）的数据。
确定 NCCP 患者与心源性胸痛（CCP）患者在临床表现、心理影响和生活质量方面的差异，并确定影响这些患者的任何因素。
在香港和中国武汉连续招募因胸痛而行冠状动脉造影检查的患者。研究纳入了 140 例造影异常和 141 例造影正常的患者。使用经过验证的胃食管反流病问卷、医院焦虑抑郁量表和 12 项简明健康调查问卷（SF-12）进行评估。
NCCP 患者报告的工作缺勤天数和社会生活受损程度与 CCP 患者相似。两组焦虑和抑郁评分无差异。有反流症状的 NCCP 患者焦虑评分较高（7.19 比 5.74，P=0.044），报告更多的社会生活中断（26%比 5%，P<0.0001），请病假更多（17%比 5%，P=0.018）。
NCCP 患者的生活质量和心理影响与 CCP 患者一样显著。有反流症状的 NCCP 患者更焦虑，工作效率和社会生活受到影响。
