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栓塞疗法治疗盆腔淤血综合征的疗效:系统评价。

Efficacy of embolotherapy for the treatment of pelvic congestion syndrome: A systematic review.

机构信息

Department of Surgery, St. John of God Subiaco, Perth, WA, Australia.

Department of Surgery, St. James's Hospital, Dublin, Ireland.

出版信息

Ir J Med Sci. 2024 Jun;193(3):1441-1451. doi: 10.1007/s11845-024-03608-6. Epub 2024 Jan 31.

DOI:10.1007/s11845-024-03608-6
PMID:38294607
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11128397/
Abstract

Pelvic congestion syndrome (PCS) poses a significant health, diagnostic, and economic challenges. Transcatheter embolisation has emerged as a promising treatment for PCS. A systematic review was performed in order to assess the safety and efficacy of transcatheter embolisation in the treatment of PCS. A systematic search of electronic databases was performed using 'PubMed', 'Embase', 'Medline (OVID)', and 'Web of Science', for articles pertaining to efficacy of embolotherapy for the treatment of pelvic congestion syndrome. A total of 25 studies were included in this systematic review with a combined total of 2038 patients. All patients included were female with a mean average age of 37.65 (31-51). Of the 25 studies, 18/25 studies reported pre- and post-procedural pelvic pain outcomes using a visual analogue scale (VAS). All studies showed a reduction in VAS post-procedure. Transcatheter embolisation had a high technical success rate (94%) and an overall complication rate of 9.0%, of which 10.4% were major and 89.6% were minor. Fifteen out of 19 (78.9%) major complications required a subsequent intervention. Transcatheter embolisation using various techniques is effective and safe in treating PCS. A low quality of evidence limits the currently available literature; however, embolisation has shown to improve symptoms in the majority of patients with low complication rates and recurrence rates.

摘要

盆腔淤血综合征(PCS)对健康、诊断和经济都构成了重大挑战。经导管栓塞已成为治疗 PCS 的一种有前途的方法。为了评估经导管栓塞治疗 PCS 的安全性和有效性,进行了系统评价。通过“PubMed”、“Embase”、“Medline(OVID)”和“Web of Science”等电子数据库系统地搜索了与栓塞疗法治疗盆腔淤血综合征疗效相关的文章。本系统评价共纳入 25 项研究,共 2038 例患者。所有纳入的患者均为女性,平均年龄为 37.65 岁(31-51 岁)。在 25 项研究中,有 18/25 项研究使用视觉模拟量表(VAS)报告了术前和术后盆腔疼痛结局。所有研究均显示术后 VAS 降低。经导管栓塞的技术成功率高(94%),总并发症发生率为 9.0%,其中 10.4%为主要并发症,89.6%为次要并发症。19 例中的 15 例(78.9%)主要并发症需要进一步干预。使用各种技术的经导管栓塞治疗 PCS 是有效且安全的。证据质量低限制了目前可用的文献;然而,栓塞治疗显示出在大多数患者中改善症状的效果,且并发症发生率和复发率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ec7/11128397/fbc4427ca9cd/11845_2024_3608_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ec7/11128397/fbc4427ca9cd/11845_2024_3608_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4ec7/11128397/fbc4427ca9cd/11845_2024_3608_Fig1_HTML.jpg

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本文引用的文献

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A systematic review highlighting poor quality of evidence for content validity of quality of life instruments in female chronic pelvic pain.系统评价强调女性慢性盆腔痛生活质量工具内容效度证据质量差。
J Clin Epidemiol. 2022 Sep;149:1-11. doi: 10.1016/j.jclinepi.2022.04.016. Epub 2022 Apr 19.
2
Embolization in pelvic venous disorders using ethylene vinyl alcohol copolymer (Onyx®) and Aetoxysclerol: a prospective evaluation of safety and long-term efficacy.使用乙烯-乙烯醇共聚物(Onyx®)和乙氧硬化醇栓塞治疗盆腔静脉疾病:安全性和长期疗效的前瞻性评估。
Eur Radiol. 2022 Jul;32(7):4679-4686. doi: 10.1007/s00330-022-08567-z. Epub 2022 Feb 8.
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Editor's Choice - European Society for Vascular Surgery (ESVS) 2022 Clinical Practice Guidelines on the Management of Chronic Venous Disease of the Lower Limbs.
编辑推荐——欧洲血管外科学会(ESVS)2022年下肢慢性静脉疾病管理临床实践指南
Eur J Vasc Endovasc Surg. 2022 Feb;63(2):184-267. doi: 10.1016/j.ejvs.2021.12.024. Epub 2022 Jan 11.
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Ovarian Vein Embolization With N-butyl-2 Cyanoacrylate Glubran-2 for the Treatment of Pelvic Venous Disorder.使用n-丁基-2-氰基丙烯酸酯(Glubran-2)进行卵巢静脉栓塞术治疗盆腔静脉疾病。
Front Surg. 2021 Dec 16;8:760600. doi: 10.3389/fsurg.2021.760600. eCollection 2021.
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