Department of Gerontology, Shandong Provincial Qianfoshan Hospital, The First Affiliated Hospital of Shandong First Medical University, 16766 Jingshi Road, Jinan, 250014, China.
Laboratory of Microvascular Medicine, Medical Research Center, Shandong Provincial Qianfoshan Hospital, Shandong University, 16766 Jingshi Road, Jinan, 250014, China.
Neurochem Res. 2024 Apr;49(4):887-894. doi: 10.1007/s11064-023-04079-4. Epub 2024 Jan 31.
A stroke is one of the most common fatal diseases of the nervous system, and the number of strokes per year has increased substantially in recent years. Epilepsy is a poststroke complication that greatly affects the prognosis of patients and reduces their quality of survival. Effective avoidance of causative factors can reduce the risk of a poststroke seizure. However, while many studies have been devoted to elucidating the pathogenesis of poststroke seizures, the literature lacks a comprehensive understanding of the pathogenic mechanism. This article briefly presents the current definition, risk factors, pathogenesis, and prognosis of poststroke seizures based on reported studies and literature reviews, aiming to enrich the available knowledge of this disease.
中风是神经系统最常见的致命疾病之一,近年来每年中风的发病率有大幅上升。癫痫是中风后的一种并发症,极大地影响了患者的预后,并降低了他们的生存质量。有效避免致病因素可以降低中风后癫痫发作的风险。然而,尽管许多研究致力于阐明中风后癫痫发作的发病机制,但文献中对其发病机制的认识还不够全面。本文基于已发表的研究和文献综述,简要介绍了中风后癫痫发作的当前定义、危险因素、发病机制和预后,旨在丰富对这种疾病的认识。