Honkanen E, Törnroth T, Pettersson E, Skrifvars B
Clin Nephrol. 1987 Feb;27(2):87-93.
In a series of 96 patients with membranous glomerulonephritis (MGN) there were 14 who had concomitant rheumatoid arthritis. Ten of these had been treated with gold or D-penicillamine; in four patients neither of these drugs could have been responsible for the MGN. One of them received intrasynovial osmium tetroxide two months before the clinical onset of MGN. Three of the patients had positive rheumatoid factor. HLA-type was examined in three patients and all showed B27 antigen but not DR3. No patient developed signs of systemic lupus erythematosus during the follow-up (mean 5.9 years). In two patients MGN persisted as judged from urinary abnormalities, one patient recovered after a relapse period and one developed secondary amyloidosis.
在一组96例膜性肾小球肾炎（MGN）患者中，有14例同时患有类风湿关节炎。其中10例曾接受金制剂或青霉胺治疗；4例患者的MGN不可能由这两种药物引起。其中1例在MGN临床发病前两个月接受了关节腔内四氧化锇注射。3例患者类风湿因子呈阳性。对3例患者进行了HLA分型检查，均显示为B27抗原阳性而非DR3。在随访期间（平均5.9年），无患者出现系统性红斑狼疮的体征。根据尿液异常判断，2例患者的MGN持续存在，1例患者在复发期后康复，1例发展为继发性淀粉样变性。
