Froes Meyer Patrícia, Dos Santos Borges Fabio, Dantas Soares Ciro, Oliveira Guerra Angelo Roncalli, Valentim da Silva Rodrigo Marcel, de Morais Carreiro Eneida, de Brito Guerra Custódio L, de Andrade Ana Laura Martins, De Oliveira Glenda Maria
Drs. Carreiro, Soares, and Meyer are with the International Research Group in Rio Grande do Norte, Brazil.
Dr. Borges is with the Universidade Estácio de Sá in Rio de Janeiro, Brazil.
J Clin Aesthet Dermatol. 2024 Jan;17(1):33-40.
The plasma jet is a non-surgical and minimally invasive procedure that acts by heating the superficial region of the skin, providing rejuvenation of the region.
We sought to compare the clinical and histological effects of direct plasma jet versus electrocarbonization without plasma in the treatment of wrinkles in the upper palpebral region.
This is a clinical trial in which 20 volunteers participated and divided into two groups: electrocarbonization (EG) and plasma jet (JPG), which were clinically evaluated before and after treatment through evaluation protocols, photographs, and questionnaires. Three treatment sessions were performed in the upper eyelid region with an interval of 30 days. After the treatment, a surgical procedure of upper blepharoplasty was performed on two volunteers to remove a skin fragment and later histological analysis.
The JPG showed better clinical responses in rejuvenation. The EG promoted an increase in the number of fibroblasts, the number of blood vessels and the amount of inflammation. The JPG showed an increase in the number of fibroblasts and blood vessels. It was observed that the JPG generated activation of T lymphocytes (CD3), macrophages (CD68), and plasmocytes (CD138); in addition to reducing the number of positive cells for CD57 (NK cells). The satisfaction analysis shows that 100 percent in the JPG considered themselves satisfied with the treatment.
We verified that in comparison with electrocarbonization, the use of a direct plasma jet promoted tissue improvement at the histological level, in addition to fewer adverse reactions.
等离子体射流是一种非手术的微创治疗方法,通过加热皮肤表层区域起作用,使该区域恢复活力。
我们试图比较直接等离子体射流与无等离子体的电碳化在上睑区域皱纹治疗中的临床和组织学效果。
这是一项临床试验,20名志愿者参与并分为两组:电碳化组(EG)和等离子体射流组(JPG)。通过评估方案、照片和问卷对两组在治疗前后进行临床评估。在上眼睑区域进行了三个疗程的治疗,间隔30天。治疗后,对两名志愿者进行上睑成形手术以切除皮肤碎片,随后进行组织学分析。
等离子体射流组在恢复活力方面显示出更好的临床反应。电碳化组促进了成纤维细胞数量、血管数量和炎症量的增加。等离子体射流组显示成纤维细胞和血管数量增加。观察到等离子体射流组激活了T淋巴细胞(CD3)、巨噬细胞(CD68)和浆细胞(CD138);此外还减少了CD57阳性细胞(自然杀伤细胞)的数量。满意度分析显示,等离子体射流组100%的人认为对治疗满意。
我们证实,与电碳化相比,使用直接等离子体射流除了不良反应较少外,还在组织学水平上促进了组织改善。