Butler T W, Gefter J, Kleto D, Shuck E H, Ruffner B W
Dis Colon Rectum. 1987 Apr;30(4):293-5. doi: 10.1007/BF02556178.
A 40-year-old black male had unresectable giant condylomata acuminata of the anorectum with invasive, squamous-cell carcinoma. He was treated with intravenous 5-fluorouracil and mitomycin-C and with extended field radiation to the primary lesion. An abdominoperineal resection was performed, and the surgical specimen contained no residual cancer. Three years after diagnosis, the patient has no recurrent cancer. This case illustrates that otherwise unresectable giant condylomata acuminata with invasive carcinoma may be rendered operable with chemotherapy and radiation.
一名40岁的黑人男性患有无法切除的直肠肛门巨大尖锐湿疣，并伴有浸润性鳞状细胞癌。他接受了静脉注射5-氟尿嘧啶和丝裂霉素-C治疗，并对原发灶进行了扩大野放射治疗。随后进行了腹会阴联合切除术，手术标本中未发现残留癌。诊断三年后，患者未出现癌症复发。该病例表明，原本无法切除的伴有浸润癌的巨大尖锐湿疣通过化疗和放疗后可能变得可以手术切除。
