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亲核膦催化：不为人知的故事。

Nucleophilic Phosphine Catalysis: The Untold Story.

作者信息

Khong San, Venkatesh Telugu, Kwon Ohyun

机构信息

Department of Chemistry and Biochemistry, University of California, Los Angeles 607 Charles E. Young Drive East, Los Angeles, CA 90095-1569 (USA).

出版信息

Asian J Org Chem. 2021 Nov;10(11):2699-2708. doi: 10.1002/ajoc.202100496. Epub 2021 Sep 2.

DOI:10.1002/ajoc.202100496
PMID:38298937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10829526/
Abstract

This Minireview provides insight into the early history of nucleophilic phosphinocatalysis. The concepts of 1,4-addition of a tertiary phosphine to an α,β-enone and of equilibrium between the resulting phosphonium zwitterion and phosphonium ylide established a fundamental basis for the development of several classical transformations, including the Rauhut-Currier, Morita, McClure-Baizer-Anderson, and Oda reactions.

摘要

本综述深入探讨了亲核膦催化的早期历史。叔膦对α,β-烯酮的1,4-加成以及所得鏻两性离子与鏻叶立德之间的平衡概念，为包括劳胡特-柯里尔反应、森田反应、麦克卢尔-拜泽尔-安德森反应和小田反应在内的几种经典转化反应的发展奠定了基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c724/10829526/85e339defac5/nihms-1950258-f0016.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c724/10829526/37780764ce03/nihms-1950258-f0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c724/10829526/ec94f886d04e/nihms-1950258-f0007.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c724/10829526/7bd8594b6a50/nihms-1950258-f0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c724/10829526/b4790019132d/nihms-1950258-f0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c724/10829526/70fe0204f9b4/nihms-1950258-f0011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c724/10829526/48e230fb3687/nihms-1950258-f0012.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c724/10829526/3c12190b4df2/nihms-1950258-f0013.jpg
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