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Gentamicin-induced alterations of intralysosomal pH and lysosomal enzyme activities.

作者信息

Oshima M, Hashiguchi M, Shindo N, Shibata S

出版信息

Dev Toxicol Environ Sci. 1986;14:91-100.

PMID:3829985
Abstract
摘要

相似文献

1
Gentamicin-induced alterations of intralysosomal pH and lysosomal enzyme activities.
Dev Toxicol Environ Sci. 1986;14:91-100.
2
Biochemical mechanisms of aminoglycoside cell toxicity. I. The uptake of gentamicin by cultured skin fibroblasts and the alteration of lysosomal enzyme activities.
J Biochem. 1986 Dec;100(6):1575-82. doi: 10.1093/oxfordjournals.jbchem.a121865.
3
Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by coadministration of poly-L-aspartic acid.通过联合给予聚-L-天冬氨酸预防庆大霉素诱导的早期肾脏改变（磷脂沉积症和DNA合成增加）。
J Pharmacol Exp Ther. 1990 Nov;255(2):858-66.
4
Gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts. Quantitative ultrastructural and biochemical study.
Lab Invest. 1979 Apr;40(4):481-91.
5
Effect of gentamicin on the lysosomal system of cultured human proximal tubular cells. Endocytotic activity, lysosomal pH and membrane fragility.庆大霉素对培养的人近端肾小管细胞溶酶体系统的影响。内吞活性、溶酶体pH值和膜脆性。
Biochem Pharmacol. 1989 Aug 1;38(15):2527-34. doi: 10.1016/0006-2952(89)90098-1.
6
Comparative toxicity of aminoglycoside antibiotics towards the lysosomes in a cell culture model.细胞培养模型中氨基糖苷类抗生素对溶酶体的比较毒性
Toxicology. 1980;17(2):195-9. doi: 10.1016/0300-483x(80)90094-3.
7
Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. II. Comparative in vitro and in vivo studies with poly-L-aspartic, poly-L-glutamic and poly-D-glutamic acids.聚天冬氨酸对庆大霉素诱导的磷脂沉积症的保护机制。II. 聚-L-天冬氨酸、聚-L-谷氨酸和聚-D-谷氨酸的体外和体内比较研究。
J Pharmacol Exp Ther. 1990 Nov;255(2):875-85.
8
Mechanism of protection afforded by polyaspartic acid against gentamicin-induced phospholipidosis. I. Polyaspartic acid binds gentamicin and displaces it from negatively charged phospholipid layers in vitro.聚天冬氨酸对庆大霉素诱导的磷脂沉积症的保护机制。I. 聚天冬氨酸在体外结合庆大霉素并将其从带负电荷的磷脂层中置换出来。
J Pharmacol Exp Ther. 1990 Nov;255(2):867-74.
9
Gentamicin-induced renal metabolic alterations in newborn rat kidney: lack of potentiation by vancomycin.庆大霉素诱导新生大鼠肾脏代谢改变：万古霉素无增强作用。
Toxicol Appl Pharmacol. 1989 Jun 1;99(1):61-71. doi: 10.1016/0041-008x(89)90111-7.
10
Gentamicin induces a lysosomal phospholipidosis in cultured rat fibroblast [proceedings].庆大霉素在培养的大鼠成纤维细胞中诱导溶酶体磷脂沉积症[会议论文集]
Arch Int Physiol Biochim. 1978 May;86(2):403-5.