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Gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts. Quantitative ultrastructural and biochemical study.

作者信息

Aubert-Tulkens G, Van Hoof F, Tulkens P

出版信息

Lab Invest. 1979 Apr;40(4):481-91.

PMID:431047
Abstract
摘要

相似文献

1
Gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts. Quantitative ultrastructural and biochemical study.
Lab Invest. 1979 Apr;40(4):481-91.
2
Gentamicin induces a lysosomal phospholipidosis in cultured rat fibroblast [proceedings].庆大霉素在培养的大鼠成纤维细胞中诱导溶酶体磷脂沉积症[会议论文集]
Arch Int Physiol Biochim. 1978 May;86(2):403-5.
3
Protection against gentamicin-induced early renal alterations (phospholipidosis and increased DNA synthesis) by coadministration of poly-L-aspartic acid.通过联合给予聚-L-天冬氨酸预防庆大霉素诱导的早期肾脏改变（磷脂沉积症和DNA合成增加）。
J Pharmacol Exp Ther. 1990 Nov;255(2):858-66.
4
Leupeptin and E-64, inhibitors of cysteine proteinases, prevent gentamicin-induced lysosomal phospholipidosis in cultured rat fibroblasts.半胱氨酸蛋白酶抑制剂亮抑酶肽和E-64可预防庆大霉素诱导的培养大鼠成纤维细胞中的溶酶体磷脂沉积症。
Toxicol Lett. 1994 Sep;73(3):201-8. doi: 10.1016/0378-4274(94)90059-0.
5
Gentamicin-induced alterations of intralysosomal pH and lysosomal enzyme activities.
Dev Toxicol Environ Sci. 1986;14:91-100.
6
Mechanism of aminoglycoside-induced lysosomal phospholipidosis: in vitro and in vivo studies with gentamicin and amikacin.氨基糖苷类诱导溶酶体磷脂沉积症的机制：庆大霉素和阿米卡星的体外和体内研究
Biochem Pharmacol. 1982 Dec 1;31(23):3861-70. doi: 10.1016/0006-2952(82)90303-3.
7
Biochemical mechanisms of aminoglycoside cell toxicity. I. The uptake of gentamicin by cultured skin fibroblasts and the alteration of lysosomal enzyme activities.
J Biochem. 1986 Dec;100(6):1575-82. doi: 10.1093/oxfordjournals.jbchem.a121865.
8
Gentamicin nephrotoxicity in rats. I. Acute biochemical and ultrastructural effects.庆大霉素对大鼠的肾毒性。I. 急性生化和超微结构效应。
Lab Invest. 1975 Oct;33(4):412-7.
9
Contrasting effects of gentamicin and mercuric chloride on urinary excretion of enzymes and phospholipids in the rat.庆大霉素和氯化汞对大鼠尿液中酶和磷脂排泄的对比作用。
Lab Invest. 1985 Apr;52(4):375-86.
10
Presence of a lysosomal enzyme, arylsulfatase-A, in the prelysosome-endosome compartments of human cultured fibroblasts.溶酶体酶芳基硫酸酯酶A在人培养成纤维细胞的前溶酶体-内体区室中的存在。
Eur J Cell Biol. 1989 Feb;48(1):71-8.

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Gentamicin causes apoptosis at low concentrations in renal LLC-PK1 cells subjected to electroporation.庆大霉素在经电穿孔处理的肾 LLC-PK1 细胞中，低浓度时会导致细胞凋亡。
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