Anderson P, Bondesson U, Mattiasson I, Johansson B W
Eur J Clin Pharmacol. 1987;31(5):625-7. doi: 10.1007/BF00606644.
The concentrations of verapamil and norverapamil have been measured in milk and plasma samples from a 32 year-old woman treated with verapamil 80 mg tds while breast-feeding her child. The average steady-state concentrations of verapamil and noverapamil in milk were, respectively, 60% and 16% of the concentrations in plasma. The breast-fed child received less than 0.01% of the dose of verapamil given to the mother. No verapamil or norverapamil (less than 1 ng/ml) could be detected in the plasma from the child.
在一名32岁正在服用维拉帕米（每日三次，每次80mg）并母乳喂养孩子的女性的乳汁和血浆样本中，已对维拉帕米和去甲维拉帕米的浓度进行了测定。乳汁中维拉帕米和去甲维拉帕米的平均稳态浓度分别为血浆浓度的60%和16%。母乳喂养的孩子所摄入的维拉帕米剂量不到母亲给药剂量的0.01%。在孩子的血浆中未检测到维拉帕米或去甲维拉帕米（浓度低于1ng/ml）。
