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1999-2019 年美国初级保健环境中开具疼痛药物处方的种族和民族差异:我们现在在哪里?

Racial and Ethnic Disparities in the Prescribing of Pain Medication in US Primary Care Settings, 1999-2019: Where Are We Now?

机构信息

Centre for Chronic Illness and Ageing, University of Greenwich, London, UK.

Centre for Inequalities, University of Greenwich, London, UK.

出版信息

J Gen Intern Med. 2024 Jul;39(9):1597-1605. doi: 10.1007/s11606-024-08638-5. Epub 2024 Feb 1.

Abstract

BACKGROUND

Policy initiatives have attempted to reduce healthcare inequalities in the USA, but evidence on whether these initiatives have reduced racial and ethnic disparities in pain treatment in primary care is lacking.

OBJECTIVE

To determine whether racial and ethnic disparities in medication prescribed for pain in primary care settings have diminished over a 21-year period from 1999 to 2019.

DESIGN

An annual, representative cross-sectional probability sample of visits to US primary care physicians, taken from the National Ambulatory Medical Care Survey.

PATIENTS

Pain-related visits to primary care physicians.

MAIN MEASURES

Prescriptions for opioid and non-opioid analgesics.

KEY RESULTS

Of 599,293 (16%) sampled visits, 94,422 were pain-related, representing a population-weighted estimate of 143 million visits made annually to primary care physicians for pain. Relative risk analysis controlling for insurance, pain type, and other potential confounds showed no difference in pain medication prescribed between Black and White patients (p = .121). However, White patients were 1.61 (95% CI 1.32-1.97) and Black patients 1.57 (95% CI 1.26-1.95) times more likely to be prescribed opioids than a more underrepresented group consisting of Asian, Native-Hawaiian/Pacific-Islander, and American-Indian/Alaska-Natives (ps < .001). Non-Hispanic/Latino patients were 1.32 (95% CI 1.18-1.45) times more likely to receive opioids for pain than Hispanic/Latino patients (p < .001). Penalized cubic spline regression found no substantive narrowing of disparities over time.

CONCLUSIONS

These findings suggest that additional intervention strategies, or better implementation of existing strategies, are needed to eliminate ethnic and racial disparities in pain treatment towards the goal of equitable healthcare.

摘要

背景

美国曾出台多项政策举措,力图减少医疗保健方面的不平等现象,但缺乏相关证据表明这些举措是否减少了初级保健中疼痛治疗的种族和民族差异。

目的

确定从 1999 年至 2019 年的 21 年间,初级保健环境中用于治疗疼痛的药物在种族和民族方面的差异是否有所缩小。

设计

一项每年在全美范围内进行的、具有代表性的初级保健医生就诊情况横断面概率抽样调查,数据来自全国门诊医疗调查。

患者

到初级保健医生处就诊的与疼痛相关的患者。

主要测量指标

阿片类药物和非阿片类镇痛药的处方。

主要结果

在所抽取的 599293 例(占 16%)就诊中,94422 例为与疼痛相关的就诊,代表每年有 1.43 亿例疼痛就诊患者到初级保健医生处就诊,这是经过人口加权估计得出的结果。在控制保险、疼痛类型和其他潜在混杂因素后进行相对风险分析,结果显示黑人和白人患者开处的疼痛药物没有差异(p=0.121)。然而,白人患者开具阿片类药物的可能性是黑人患者的 1.61 倍(95%CI 1.32-1.97),而黑人患者开具阿片类药物的可能性是亚裔、美属萨摩亚/太平洋岛民和美洲印第安人/阿拉斯加原住民患者的 1.57 倍(p<0.001)。非西班牙裔/拉丁裔患者开具阿片类药物治疗疼痛的可能性比西班牙裔/拉丁裔患者高 1.32 倍(95%CI 1.18-1.45)(p<0.001)。惩罚三次样条回归发现,随着时间的推移,差异并没有实质性缩小。

结论

这些发现表明,需要采取更多的干预策略,或更好地实施现有策略,以消除在疼痛治疗方面的种族和民族差异,朝着公平医疗保健的目标迈进。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2bf/11254888/bf0b7be1baec/11606_2024_8638_Fig1_HTML.jpg

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