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社会人口统计学特征及其与宫颈癌患者生存的关系。

Sociodemographic characteristics and their association with survival in women with cervical cancer.

机构信息

Department of Clinical Research, Instituto Nacional de Cancerología, Av. San Fernando No. 22, Sección XVI, 14080, Mexico City, Tlalpan, Mexico.

MICAELA Program, Instituto Nacional de Cancerología, Mexico City, Mexico.

出版信息

BMC Cancer. 2024 Feb 1;24(1):161. doi: 10.1186/s12885-024-11909-3.

Abstract

BACKGROUND

In 2020, the highest incidence and mortality from cervical cancer (CC) were detected in low and middle-income countries. CC remains a health problem for women living in them. In Mexico, CC ranks second in cancer incidence and mortality in women. The main characteristics of this population are low income, low educational level, and inadequate medical coverage. The present study characterized the Mexican population by CC, and the sociodemographic variables that impacted overall survival (OS) were identified.

METHODS

A retrospective study that included a cohort of patients with a confirmed diagnosis of CC at the Instituto Nacional de Cancerologia between 2003 and 2016. Information was collected on sociodemographic variables related to the disease and OS.

RESULTS

Four thousand six hundred thirty-one patients were included. The median age was 51 years, 78.5% were unemployed, 44.4% lived in a rural/suburban area, 50.8% had a partner when collecting this information, and 74.3% were classified as having low socioeconomic status. Age, living in a rural/suburban area, more advanced stages of the disease, and not receiving cancer treatment were associated with lower OS.

CONCLUSION

CC continues to affect mainly women with minimal resources, low educational levels, and living in marginalized areas. These characteristics influence the OS. Prevention and timely detection programs, education, and training focused on this population and with broader coverage are required to identify patients with CC at earlier stages.

摘要

背景

2020 年,宫颈癌(CC)发病率和死亡率最高的国家为中低收入国家。宫颈癌仍然是这些国家女性的健康问题。在墨西哥,宫颈癌在女性癌症发病率和死亡率中排名第二。该人群的主要特征是收入低、教育水平低、医疗保障不足。本研究对墨西哥 CC 人群进行了特征描述,并确定了影响总生存率(OS)的社会人口统计学变量。

方法

这是一项回顾性研究,纳入了 2003 年至 2016 年间在国立癌症研究所确诊为 CC 的患者队列。收集了与疾病和 OS 相关的社会人口统计学变量信息。

结果

共纳入 4631 名患者。中位年龄为 51 岁,78.5%为失业者,44.4%居住在农村/郊区,50.8%在收集信息时有伴侣,74.3%被归类为社会经济地位较低。年龄、居住在农村/郊区、疾病更晚期以及未接受癌症治疗与较低的 OS 相关。

结论

CC 仍然主要影响资源有限、教育水平低且生活在边缘地区的女性。这些特征影响 OS。需要针对这一人群开展预防和及时发现计划、教育和培训,并扩大覆盖范围,以便更早发现 CC 患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a34f/10832171/8b4aad7cdc39/12885_2024_11909_Fig1_HTML.jpg

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