Matsumura Tomonori, Koide Norimasa, Matsushima Takahiro, Wada Ryuichi, Iwasaki Kenichi, Kitamura Kenta, Usui Shinsuke, Koyama Motoi, Kozaki Kouichi, Sato Yoshinobu, Karikomi Kazuhiro, Suwa Tatsushi
Dept. of Surgery, Kashiwa Kousei General Hospital.
Gan To Kagaku Ryoho. 2023 Dec;50(13):1644-1646.
Monomorphic epitheliotropic intestinal T-cell lymphoma(MEITL)is very rare and aggressive subtype of lymphoma with poor prognosis. A 60-year-old man complaining of abdominal pain was underwent partial resection of the jejunum for panperitonitis with a small intestinal perforation. The histopathological and immunohistochemical findings led to the diagnosis of MEITL. Postoperative course was uneventful. One month after the operation, the patient was scheduled for 6 courses of CHOP regimens. He presented with bowel obstruction twice during the 3 courses of CHOP. As the recurrence of MEITL could not be ruled out, diagnostic laparoscopy was performed. Laparoscopic findings revealed no recurrence and adhesive small bowel obstruction. The patient was followed closely without treatment after 6 courses of CHOP. The patient has been alive without recurrence 18 months after the resection. We reported a case of monomorphic epithelial intestinal T- cell lymphoma causing jejunal perforation.
单形性上皮趋化性肠道T细胞淋巴瘤（MEITL）是一种非常罕见且侵袭性强、预后不良的淋巴瘤亚型。一名60岁男性因小肠穿孔并发全腹膜炎接受了空肠部分切除术，术后组织病理学和免疫组化检查结果确诊为MEITL。术后恢复顺利。术后1个月，患者计划接受6个疗程的CHOP方案化疗。在CHOP方案化疗的3个疗程中，患者两次出现肠梗阻。由于不能排除MEITL复发，遂进行了诊断性腹腔镜检查。腹腔镜检查结果显示无复发，为粘连性小肠梗阻。6个疗程的CHOP方案化疗后，患者未接受治疗，密切随访。切除术后18个月，患者仍存活且无复发。我们报告了一例导致空肠穿孔的单形性上皮肠道T细胞淋巴瘤病例。
