Department of Pulmonary Medicine, School of Medicine, Fukushima Medical University, Japan.
Intern Med. 2020 Oct 15;59(20):2559-2563. doi: 10.2169/internalmedicine.4710-20. Epub 2020 Jul 7.
Monomorphic epitheliotropic intestinal T-cell lymphoma (MEITL) is a primary intestinal T-cell lymphoma and other organ involvement is very rare. A rare case of MEITL involving the lung and brain is herein reported. The patient developed panperitonitis with a small intestinal perforation, and emergency surgery was performed. The pathological findings from the surgical specimens demonstrated atypical lymphoid cells which were positive for CD3, CD8, and CD56. Moreover, the pathological findings of lung specimens taken by bronchoscopy were consistent with those of the small intestine. It is therefore important to include the possibility of MEITL in the differential diagnosis of cancer patients.
单一表型上皮嗜性肠 T 细胞淋巴瘤(MEITL)是一种原发性肠 T 细胞淋巴瘤,其他器官受累非常罕见。本文报告了一例罕见的累及肺和脑的 MEITL 病例。该患者发生全腹膜炎伴小肠穿孔,行急诊手术。手术标本的病理检查显示非典型淋巴样细胞 CD3、CD8 和 CD56 阳性。此外,支气管镜检查获得的肺标本的病理检查结果与小肠一致。因此,在癌症患者的鉴别诊断中,应考虑 MEITL 的可能性。