Azerbaijan Medical University, Baku, Azerbaijan.
Department of Anesthesiology, Besat Hospital, Hamadan University of Medical Sciences, Hamadan, Iran.
Endocr Metab Immune Disord Drug Targets. 2024;24(13):1488-1505. doi: 10.2174/0118715303265274231204075802.
The respiratory illness known as COVID-19 is caused by the novel coronavirus, SARS-CoV-2. While the precise pathogenic mechanism of COVID-19 remains unclear, the occurrence of a cytokine storm subsequent to viral infection plays a pivotal role in the initiation and advancement of the disease. The infection of SARS-CoV-2 induces a state of immune system hyperactivity, leading to an excessive production of inflammatory cytokines. Consequently, the identification of the various signaling pathways implicated in the inflammation induced by COVID-19 will enable researchers to investigate new targets for therapeutic intervention.
被称为 COVID-19 的呼吸道疾病是由新型冠状病毒 SARS-CoV-2 引起的。虽然 COVID-19 的确切发病机制尚不清楚，但病毒感染后继发的细胞因子风暴在疾病的发生和进展中起着关键作用。SARS-CoV-2 的感染会引起免疫系统过度活跃，导致炎症细胞因子过度产生。因此，鉴定 COVID-19 引起的炎症相关的各种信号通路，将使研究人员能够发现新的治疗靶点。
